Demonstration of a Common Antigen Between Schistosoma Mansoni and Fasciola Hepatica

Ronald P. Pelley Division of Geographic Medicine, Department of Medicine, Case Western Reserve University and University Hospitals, Department of Biology, University of Puerto Rico, Cleveland, Ohio 44106

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George V. Hillyer Division of Geographic Medicine, Department of Medicine, Case Western Reserve University and University Hospitals, Department of Biology, University of Puerto Rico, Cleveland, Ohio 44106

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The presence of a common antigen between Schistosoma mansoni eggs and Fasciola hepatica adult worms was demonstrated by utilizing an anti-S. mansoni adult worm antiserum. Although not one of the three major serologic S. mansoni egg antigens, its complete cross-reactivity suggests that serologic tests done with these crude antigenic extracts will result in many false-positive cases in areas where both parasites are endemic.

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