Streptocerciasis: Degeneration of Adult Dipetalonema Streptocerca in Man Following Diethylcarbamazine Therapy

Wayne M. Meyers Department of Infectious and Parasitic Diseases Pathology, Armed Forces Institute of Pathology, Iyonda, Washington, D.C. 20306, Republic of Zaire

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Roger Moris Department of Infectious and Parasitic Diseases Pathology, Armed Forces Institute of Pathology, Iyonda, Washington, D.C. 20306, Republic of Zaire

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Ronald C. Neafie Department of Infectious and Parasitic Diseases Pathology, Armed Forces Institute of Pathology, Iyonda, Washington, D.C. 20306, Republic of Zaire

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Daniel H. Connor Department of Infectious and Parasitic Diseases Pathology, Armed Forces Institute of Pathology, Iyonda, Washington, D.C. 20306, Republic of Zaire

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Jacques Bourland Department of Infectious and Parasitic Diseases Pathology, Armed Forces Institute of Pathology, Iyonda, Washington, D.C. 20306, Republic of Zaire

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Thirty-three patients in Zaire with streptocerciasis were treated daily with diethylcarbamazine (DEC) for 21 days. Histopathologic studies of biopsy specimens from papules of skin established that during DEC treatment adult male and female Dipetalonema streptocerca die and degenerate. DEC may thus produce radical cures of streptocerciasis.

Author Notes

Present address: Damien Foundation, B.P. 774, Bujumbura, Republic of Burundi.

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