Resistance of Mice to Secondary Infection with Schistosoma Mansoni

I. Comparison of Bisexual and Unisexual Initial Infections

D. A. Dean Immunoparasitology Department, Naval Medical Research Institute, American Foundation for Biological Research, Bethesda, Maryland

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P. Minard Immunoparasitology Department, Naval Medical Research Institute, American Foundation for Biological Research, Bethesda, Maryland

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M. A. Stirewalt Immunoparasitology Department, Naval Medical Research Institute, American Foundation for Biological Research, Bethesda, Maryland

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W. E. Vannier Immunoparasitology Department, Naval Medical Research Institute, American Foundation for Biological Research, Bethesda, Maryland

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K. D. Murrell Immunoparasitology Department, Naval Medical Research Institute, American Foundation for Biological Research, Bethesda, Maryland

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DOI:
https://doi.org/10.4269/ajtmh.1978.27.951
Volume/Issue:
Volume 27: Issue 5
Page(s):
951–956
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Mice receiving a unisexual primary infection with either sex of Schistosoma mansoni did not develop detectable resistance to reinfection. In contrast, mice receiving a bisexual primary infection developed a high degree of resistance. The number of adult worms developing from the challenge infection was reduced, relative to controls, by 72–100% at challenge times of 6 weeks or greater.
Copyright:
Copyright © 1978 by The American Society of Tropical Medicine and Hygiene 1978
Accepted:
25 Mar 1978
|
Published Online:
Sep 1978
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
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