Renal Amyloidosis with Nephrotic Syndrome in Two Patients with Schistosomiasis Mansoni and Chronic Salmonellosis

L. J. Strausbaugh U.S. Naval Medical Research Unit No. 3, Cairo, Arab Republic of Egypt

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Z. Farid U.S. Naval Medical Research Unit No. 3, Cairo, Arab Republic of Egypt

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G. I. Higashi U.S. Naval Medical Research Unit No. 3, Cairo, Arab Republic of Egypt

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S. Bassily U.S. Naval Medical Research Unit No. 3, Cairo, Arab Republic of Egypt

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DOI:
https://doi.org/10.4269/ajtmh.1978.27.919
Volume/Issue:
Volume 27: Issue 5
Page(s):
919–923
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This report describes two Egyptian patients who presented with the nephrotic syndrome and concurrent infections with Schistosoma mansoni and Salmonella paratyphi A. Unlike similar cases previously reported from this unit, these patients did not respond to antimicrobial and antischistosomal therapy, and their renal biopsies demonstrated amyloidosis. These two case reports and several experimental observations suggest that chronic schistosomiasis and salmonellosis may lead to secondary amyloidosis in susceptible individuals.

Author Notes

Copyright:
Copyright © 1978 by The American Society of Tropical Medicine and Hygiene 1978
Accepted:
11 Mar 1978
|
Published Online:
Sep 1978
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
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