Acute Renal Failure Following Scorpion Sting

K. K. Malhotra All India Institute of Medical Sciences, Jundi Shapur University School of Medicine, New Delhi-110016, India

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J. S. Chadha All India Institute of Medical Sciences, Jundi Shapur University School of Medicine, New Delhi-110016, India

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M. Mirdehghan All India Institute of Medical Sciences, Jundi Shapur University School of Medicine, New Delhi-110016, India

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H. D. Tandon All India Institute of Medical Sciences, Jundi Shapur University School of Medicine, New Delhi-110016, India

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Fifteen cases of acute renal failure following scorpion sting were studied. The onset of disease was characterized by the occurrence of hemoglobinuria within 24 h of the sting. Most of the patients developed oliguria, edema, hemolytic anemia, and hemolytic jaundice. Renal failure developed within a few days after the sting, and in five patients was severe enough to need dialysis. The onset of diuresis in oliguric patients occurred between 6 and 21 days following the sting. Renal biopsies were possible in four cases and showed mesangial proliferation, variable degrees of tubular changes, and mild interstitial infiltration. The pathogenesis of acute renal failure in these patients is discussed.

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