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Strongyloides Ratti Infections in Rats
I. Immunopathology
C. Erik Olson
C. Erik Olson
Department of Pathobiology, Johns Hopkins School of Hygiene and Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205
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Everett L. Schiller
Everett L. Schiller
Department of Pathobiology, Johns Hopkins School of Hygiene and Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205
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The elimination of adult parasites from the intestines of rats after a first and second infection of Strongyloides ratti was studied. Expulsion after a second infection was anamnestic, indicating that the response is immunologic. Intestinal mast cell responses accompanied damage and expulsion of worms, the secondary mast cell response being more rapid but less intense than the first. Antithymocyte serum suppressed expulsion as well as both the intestinal mast cell and circulating eosinophil responses to primary infection.
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| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 460 | 177 | 3 |
| Full Text Views | 10 | 0 | 0 |
| PDF Downloads | 6 | 0 | 0 |