Tissue Eosinophil Proliferation and Maturation in Schistosome-Infected Mice and Hamsters

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  • Departments of Pathology, Harvard Medical School and Peter Bent Brigham Hospital, Boston, Massachusetts 02115

Extramedullary eosinophilopoiesis is described as a regular pathological feature of murine and cricetine schistosome infections. Using the Dominici staining technique, colonies of developing eosinophils were commonly found in certain tissue sites of dense oviposition, particularly in the liver, and in associated lymphoreticular tissues. The relationship of these observations to the role of eosinophilic leukocytes in schistosomiasis is discussed.

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