The Seroepidemiology of Malaria in Middle America

IV. Passage of Malaria Antibodies from Mothers to Infants

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  • Central American Research Station, Bureau of Tropical Diseases, Center for Disease Control, Public Health Service, U.S. Department of Health, Education, and Welfare, San Salvador, El Salvador

In an area of El Salvador moderately endemic for malaria, use of the indirect fluorescent antibody test (IFA) showed that 44% of the infants born to mothers who had IFA responses to Plasmodium vivax of 1:20 or higher during the latter part of their pregnancy had positive IFA responses of 1:10 or higher to this antigen. No serum from an infant was positive in the absence of some level of malarial response in the mother.

Author Notes

Present address: Bureau of Tropical Diseases, Center for Disease Control, 1600 Clifton Road, Atlanta, Georgia 30333.

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