Elution of Renal Antischistosome Antibodies in Human Schistosomiasis Mansoni

Pamela L. Moriearty International Health Program, University of Maryland School of Medicine, Faculty of Medicine, Department of Pathology, Federal University of Bahia, Baltimore, Maryland 21201, Brazil

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Edilson Brito International Health Program, University of Maryland School of Medicine, Faculty of Medicine, Department of Pathology, Federal University of Bahia, Baltimore, Maryland 21201, Brazil

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Elution of complexed immunoglobulins was carried out on renal tissue obtained at autopsy from schistosomiasis mansoni and control cases. Substantial amounts of IgG were found in acid eluates of 2 of 5 schistosomiasis cases and 2 of 3 controls. The IgG from schistosomiasis cases produced specific indirect immunofluorescence reactions in gut and tegument of sections of adult Schistosoma mansoni; no reactivity was present against egg granulomas, cercariae, or mouse liver tissue. Control case eluates produced no fluorescence with S. mansoni antigens.

Author Notes

Research Associate, IRAP, University of Maryland ICMR.

Address reprint requests to: Dr. Palmela L. Morietary, c/o International Health Program, University of Maryland School of Medicine, 660 West Redwood Street, Baltimore, Maryland 21201.

 

 

 

 
 
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