Onchocerciasis: Invasion of Deep Organs by Onchocerca Volvulus

Autopsy Findings

Wayne M. MeyersArmed Forces Institute of Pathology, Washington, D.C. 20306

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Ronald C. NeafieArmed Forces Institute of Pathology, Washington, D.C. 20306

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Daniel H. ConnorArmed Forces Institute of Pathology, Washington, D.C. 20306

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Autopsies of two patients with onchocerciasis in the Republic of Zaïre are reported. In one patient with elephantiasis who died following diethylcarbamazine therapy there were large numbers of microfilariae of Onchocerca volvulus in the kidney, liver, pancreas, and lung. In the second patient, who also had leprosy and hyperinfection strongyloidiasis, we found an encapsulated adult O. volvulus in the wall of the thoracic aorta.

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