Antibiotic Susceptibility of Staphylococcus aureus in Saigon, South Vietnam

View More View Less
  • Infectious Disease Section, Department of Medicine, University of Oklahoma Health Sciences Center and Veterans Administration Hospital, Department of Tropical Medicine and Medical Microbiology, University of Hawaii School of Medicine, Faculty of Medicine, University of Saigon, Oklahoma City, Oklahoma 73104, South Vietnam

Methicillin resistant staphylococci are unevenly distributed throughout the world; the explanation for this is not known. During a survey of local hospitals for methicillin resistance, a number of strains from South Vietnam became available for study. Tests were performed in microtiter plates using various concentrations of several antibiotics with a final concentration of organisms of 105/ml and 108/ml. With the larger number of organisms in the inoculum, 17% of strains required 12.5 µg/ml or more of methicillin for inhibition. This is in contrast to a very low percentage of methicillin resistant staphylococci from local sources encountered in our laboratory. An unexpected finding was the occurrence of considerable lincomycin resistance in staphylococci from South Vietnam.