| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1082 | 812 | 271 |
| Full Text Views | 5 | 1 | 0 |
| PDF Downloads | 3 | 2 | 0 |
Immunizing Efficacy of a Kenyan Strain of Schistosoma Mansoni in Rhesus Monkeys (Macaca Mulatta)
Raymond T. Damian
Raymond T. Damian
Department of Zoology, University of Georgia, Athens, Georgia 30602
Search for other papers by Raymond T. Damian in
Current site
Google Scholar
PubMed
Search for other papers by Raymond T. Damian in
Current site
Google Scholar
PubMed
Nathan D. Greene
Nathan D. Greene
Department of Zoology, University of Georgia, Athens, Georgia 30602
Search for other papers by Nathan D. Greene in
Current site
Google Scholar
PubMed
Search for other papers by Nathan D. Greene in
Current site
Google Scholar
PubMed
Katherine Fitzgerald Meyer
Katherine Fitzgerald Meyer
Department of Zoology, University of Georgia, Athens, Georgia 30602
Search for other papers by Katherine Fitzgerald Meyer in
Current site
Google Scholar
PubMed
Search for other papers by Katherine Fitzgerald Meyer in
Current site
Google Scholar
PubMed
The efficacy as an immunizing agent of the Kenyan strain of Schistosoma mansoni against challenge infection in rhesus monkeys was demonstrated. An initial exposure of 200 cercariae immunized monkeys against a challenge dose of 2,000 cercariae administered 16 weeks later. The penetration rate in rhesus monkeys was 99%, the same as in baboons. The prolongation of the time for immunity to develop in baboons, compared to rhesus monkeys, shown with this strain of S. mansoni is therefore not due to a reduced potential for immunization by this strain in the rhesus monkey.
Author Notes
Southwest Foundation for Research and Education, San Antonio, Texas 78228.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1082 | 812 | 271 |
| Full Text Views | 5 | 1 | 0 |
| PDF Downloads | 3 | 2 | 0 |