Malarial Antibodies Measured by the Indirect Hemagglutination Test in West African Children

Henry M. MathewsCenter for Disease Control, Public Health Service, U.S. Department of Health, Education, and Welfare, Atlanta, Georgia 30333

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H. O. LobelCenter for Disease Control, Public Health Service, U.S. Department of Health, Education, and Welfare, Atlanta, Georgia 30333

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Joel G. BremanCenter for Disease Control, Public Health Service, U.S. Department of Health, Education, and Welfare, Atlanta, Georgia 30333

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The indirect hemagglutination test with Plasmodium falciparum antigen was used to measure malarial antibodies in filter paper blood specimens from 527 West African children. A slight decline in antibodies was noted in 6- to 8-month-old children who had no malaria parasites in their blood smears. Children older than 10 months had similar antibody levels regardless of the presence or absence of demonstrated parasites in blood smears.

Author Notes

Bureau of Laboratories.

Bureau of Smallpox Eradication, attached to O.C.C.G.E., Bobo-Dioulasso, Upper Volta.

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