Chloroquine Sensitivity of Plasmodium Falciparum in Ethiopia

II. Results of an In Vitro Test

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  • U.S. Naval Medical Research Unit No. 5, Addis Ababa, Ethiopia

Field trials were performed in two areas of Ethiopia with the Rieckmann in vitro test for chloroquine sensitivity of Plasmodium falciparum. Blood cultures from 82 test subjects showed growth of trophozoites to the schizont stage in control vials. Growth in test vials occurred in 21 cultures incubated with chloroquine at concentrations of 0.5 nanomoles or more per ml of blood. In vitro results confirm previous results obtained with an in vivo test.

Author Notes


HMC, USN, U.S. Naval Hospital, Millington, Tennessee 38054.

Mailing address: U.S. Naval Medical Research Unit No. 5, APO New York 09319.