The Relative Resistance of Dengue-Immune Monkeys to Yellow Fever Virus

Max Theiler Yale Arbovirus Research Unit, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510

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C. R. Anderson Yale Arbovirus Research Unit, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510

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Dengue-immune rhesus monkeys were challenged with a South American and two African strains of yellow fever virus. Levels of viremia were reduced as compared with control nonimmunized monkeys. The results support the hypothesis that immunity to dengue in a human population acts as a barrier to establishment of yellow fever in that population.

Author Notes

Deceased.

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