Double Blind Study with a New Nitromidazole Derivative, Ro 7-0207, Versus Metronidazole in Symptomatic Intestinal Amebiasis

David Botero R. Department of Parasitology, School of Medicine, University of Antioquia, Medellin, Colombia

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Of 115 patients with symptomatic intestinal amebiasis, 56 were treated with Ro 7-0207 and 59 with metronidazole in a double blind study. Results of treatment were similar in the two groups and side effects were of low intensity except in one patient who received Ro 7-0207 and developed numbness of hands and tongue, difficulty in speaking, and headache. These symptoms disappeared after termination of treatment.