Author:
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 229 | 95 | 4 |
| Full Text Views | 9 | 4 | 1 |
| PDF Downloads | 5 | 3 | 1 |
Comparative histopathology of two strains of Bolivian hemorrhagic fever virus infections in suckling hamsters
Timothy G. Terrell
Timothy G. Terrell
U. S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland 21701
Search for other papers by Timothy G. Terrell in
Current site
Google Scholar
PubMed
Search for other papers by Timothy G. Terrell in
Current site
Google Scholar
PubMed
James L. Stookey
James L. Stookey
U. S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland 21701
Search for other papers by James L. Stookey in
Current site
Google Scholar
PubMed
Search for other papers by James L. Stookey in
Current site
Google Scholar
PubMed
Richard O. Spertzel
Richard O. Spertzel
U. S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland 21701
Search for other papers by Richard O. Spertzel in
Current site
Google Scholar
PubMed
Search for other papers by Richard O. Spertzel in
Current site
Google Scholar
PubMed
Ralph W. Kuehne
Ralph W. Kuehne
U. S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland 21701
Search for other papers by Ralph W. Kuehne in
Current site
Google Scholar
PubMed
Search for other papers by Ralph W. Kuehne in
Current site
Google Scholar
PubMed
The histopathology of Machupo virus infection in intracerebrally inoculated suckling hamsters was studied and compared to the histopathology of a virus isolated from a case of hemorrhagic fever from Cochabamba, Bolivia. Both virus isolates were pathogenic for suckling hamsters; however, Machupo virus killed the hamsters earlier than Cochabamba virus. Lesions were most commonly observed in liver and lymphoid and central nervous systems. The lesions varied in incidence, time of occurrence and severity. A nonsuppurative encephalitis which developed in the Cochabamba-virus-infected hamsters was not a consistent finding in the animals inoculated with Machupo virus.
Author Notes
Pathology Division, U. S. Army Medical Research Institute of Infectious Diseases.
Animal Assessment Division, U. S. Army Medical Research Institute of Infectious Diseases.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 229 | 95 | 4 |
| Full Text Views | 9 | 4 | 1 |
| PDF Downloads | 5 | 3 | 1 |