Charles Bowesman, O.B.E., B.A., M.D., F.R.C.S.E., F.A.C.S., D.T.M.&H., Editor. 1st edition, 1068 + viii pages, illustrated. Edinburgh and London, E. & S. Livingstone Ltd. (The Williams & Wilkins Co., Baltimore, exclusive U.S. agents), 1960. $22.50
The radical curative efficacy of the 5-day primaquine regimen for vivax malaria was assessed in nonimmune volunteers infected with a West Pakistan strain of Plasmodium vivax. Treatment of each primary attack was with chloroquine, 1,500 mg base followed by primaquine, 15 mg base daily for 5 consecutive days. There was a 100% failure rate of radical cure for the 5-day primaquine regimen. Data on the pattern of relapse activity for this strain are included.
Formerly Head, Section on Primate Malaria, Laboratory of Parasitic Diseases, National Institutes of Health, Atlanta-Chamblee, Georgia.