Some new Nitroimidazole Derivatives

Clinical Trials in Amebic Liver Abscess

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  • Amoebiasis Research Unit, Institute for Parasitology,, Department of Medicine, University of Natal, Durban, , South Africa

Clinical trials in amebic liver abscess of three new metronidazole derivatives, nitrimidazine, tinidazole and Ro 7-0207 are reported. While all showed activity to a varying degree, none appeared to be an advance on metronidazole.

Author Notes

The Amoebiasis Research Unit is sponsored by the following bodies: The South African Medical Research Council; The Natal Provincial Administration; The University of Natal; The United States Public Health Service (Grant AI 09654-02).