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The first case of human pentastomiasis in Canada is reported in a 47-year-old man who emigrated from Hungary in 1957. Examination of an excised mesenteric lymph node revealed at least two degenerating nymphs, probably of Linguatula serrata, enclosed in fibrous tissue. One of the nymphs measured 3 mm in length and 0.2 mm in maximum diameter. On a portion of intact cuticle there were 135 to 155 backwardly directed nib-like spines which measured 18 to 22 µ in length; the sloughed cuticle was segmented. The host reaction to the parasite included generalized tissue eosinophilia with exceptionally large Charcot-Leyden crystals.