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Australia/SH Antigen and Immunoglobulins in an Epidemic of Viral Hepatitis
In an epidemic of viral hepatitis caused by polluted water, 97 of 981 persons examined showed evidence of hepatitis. None of these 97 persons gave evidence of infection with Australia/SH antigen. In 26 persons randomly selected from those with hepatitis, immunoglobulin (IgG and IgM) levels were significantly elevated. We concluded that the causative agent of this short-incubation period hepatitis, which resembled infectious hepatitis, was antigenically different from Australia/SH antigen.