Pathologic Effects of Schistomiasis in Ibadan, Western State of Nigeria

II. Pathogenesis of Lesions of the Bladder and Ureters

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  • Departments of Pathology, Peter Bent Brigham Hospital and Harvard Medical School, Departments of Pathology, University College Hospital and University of Ibadan, Boston, Massachusetts, Nigeria

One hundred thirty-five cases of urinary schistosomiasis found in 637 unselected autopsies from Ibadan, Nigeria, were studied by macroscopic and microscopic examination, urography, and tissue digestion techniques. The macroscopic and microscopic appearance of urinary tract lesions due to Schistosoma haematobium are described. Evidence favoring progression of schistosomal lesions from polypoid patches to sandy patches is presented, and changes in tissue egg-load with progression are described. A direct relation was found between intensity of infection, severity of disease, and prevalence of complications. Determinants of obstructive uropathy in urinary schistosomiasis are evaluated.

Author Notes

Department of Pathology, Peter Bent Brigham Hospital, 721 Huntington Avenue, Boston, Massachusetts 02115.

Department of Pathology, University College Hospital, Ibadan, Nigeria.

Department of Pathology, University of Ibadan, Ibadan, Nigeria.

Present address: Winnipeg General Hospital, 700 William Avenue, Winnipeg 3, Manitoba, Canada.

Present address: NAMRU-3, Cairo, Egypt, FPO New York, N. Y. 09527.

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