By P. B. Bhattacharya. Second Edition. Revised, Re-written, Enlarged and Brought Up to Date. By J. C. Banerjea, M.B. (Cal.), M.R.C.P. (Lond.) and P. B. Bhattacharya, M.B., D.T.M. (Cal.). Bengal Medical Service, Upper. Pp. I–X. 1–413. U. N Dhur & Co., Calcutta. 1938
by George Cheever Shattuck, M.D., Professor of Tropical Medicine, Emeritus, Harvard Medical School and School of Public Health. 803 pp., illustrated. Cloth. New York: Appleton-Century-Crofts, Ind. 1951. Price $10.00
Sixty-two children infected with Ascaris lumbricoides were treated with a single dose (5 mg per pound) of pyrantel pamoate. Fifty-three (85.5%) were cured as judged by a negative, direct fecal smear and ZnSO4 concentrate one week after treatment. Egg counts were much reduced in the remaining positive cases. A 2-day regimen (5 mg per lb daily) cured 37 of 38 (97.4%) Ascaris-infected children. Forty-three patients with hookworm infections were given 5 mg per pound of pyrantel on 3 consecutive days. Cure was achieved in 36 (83.7%) patients. The drug produced only mild side-effects. The chief complaint was low-grade abdominal cramp during the time when the ascarids were being expelled. There were no abnormal changes in the urinalysis, SGOT, or the serum bilirubin levels after single- or triple-dose regimens.