Lassa Fever, a New Virus Disease of Man from West Africa

IV. Electron Microscopy of Vero Cell Cultures Infected with Lassa Virus

R. W. SpeirYale Arbovirus Research Unit, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510

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O. WoodYale Arbovirus Research Unit, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510

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H. LiebhaberYale Arbovirus Research Unit, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510

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S. M. BuckleyYale Arbovirus Research Unit, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510

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Vero cell cultures infected with Lassa virus contained pleomorphic particles of variable size, with surface projections and with one or more electron-dense granules lying within the particles. These particles resemble those previously described in cell cultures infected with lymphocytic choriomeningitis virus, Machupo virus, and Tacaribe virus.

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