Niclosamide Treatment of Cestodiasis

Clinical Trials in the United States

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  • Parasitic Disease Drug Service, Parasitic Diseases Branch, Epidemiology Program, National Communicable Disease Center (NCDC), Health Services and Mental Health Administration, U. S. Public Health Service, Atlanta, Georgia 30333
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Niclosamide was given to 81 patients with tapeworm infection. Forty-seven patients received adequate follow-up, and 46 were cured; 17 of these had previously shown no improvement with quinacrine. Results indicate that niclosamide is a safe, simple, and effective agent against infection with Taenia saginata, Diphyllobothrium latum, and Hymenolepis nana.