Schistosoma Mansoni Homogenate for Active Immunization of Mice

Luiz C. Da SilvaDivision of Liver Diseases, Instituto de Medicina Tropical de São Paulo, and Division of Immunochemistry, Departamento de Microbiologia e Imunologia, Faculdade de Medicina de Universidade de São Paulo, S. Paulo, Brasil

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Rubens G. FerriDivision of Liver Diseases, Instituto de Medicina Tropical de São Paulo, and Division of Immunochemistry, Departamento de Microbiologia e Imunologia, Faculdade de Medicina de Universidade de São Paulo, S. Paulo, Brasil

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Summary

Mice infected with Schistosoma mansoni were immunized with a saline-solution extract of adult worms. Mortality in mice so immunized was compared with that in a control group of infected mice treated with saline solution. Mortality in the immunized group was about three times lower than in the nonimmunized mice.

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