Bithionol Treatment in Cerebral Paragonimiasis

Shin Joong Oh Department of Neurology, National Medical Center, Seoul, Korea

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We have reported our experience in the treatment of 24 cases of cerebral paragonimiasis with bithionol, summarizing two illustrative cases. Cure of the concomitant pulmonary infection was obtained in 22 of 24 cases. Bithionol was effective in acute phases of cerebral paragonimiasis, this being evidenced by ophthalmologic and meningeal signs. The drug was not effective in chronic stabilized cases. For maximum clinical improvement, repeated therapy was needed in three cases. One case of hepatitis caused by bithionol is reported. However, over-all toxicity of bithionol was minimal.

Author Notes

Present address: Department of Neurology, Georgetown University Hospital; 3800 Reservoir Road, N.W., Washington, D. C., 20007.