Mosquito-Induced Infection with Equine Encephalomyelitis Virus in Dogs

W. S. BivinU. S. Army Medical Unit and Fort Detrick, Frederick, Maryland 21701

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C. BarryU. S. Army Medical Unit and Fort Detrick, Frederick, Maryland 21701

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A. L. Hogge Jr.U. S. Army Medical Unit and Fort Detrick, Frederick, Maryland 21701

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E. C. CorristanU. S. Army Medical Unit and Fort Detrick, Frederick, Maryland 21701

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Summary

Dogs infected with Venezuelan equine encephalomyelitis virus via the bite of infected Aedes triseriatus responded with fever and hemagglutination-inhibiting antibodies. Even though high temperatures were elicited in 14 of the animals, in only seven did viremia develop above 102.5 mouse intraperitoneal median lethal dose50 per ml. Sufficient quantities of mosquitoes were infected from the dogs to permit passage of the virus on to guinea pigs. There were no other clinical signs of illness observed in the animals.

Author Notes

Present address: 106 Texas, Columbia, Missouri 65201.

Present address: Civil Defense Material Division, DSAH-OTR, Defense Supply Agency, Cameron Station, Alexandria, Virginia 22314.

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