By Richard C. Holcomb, M.D., F.A.C.S., Captain, Medical Corps, U. S. Navy, Retired. With Introduction by C. S. Butler, A.B., M.D., Li.D., Rear Admiral, Medical Corps, U. S. Navy. Pp. 1-189. Froben Press. New York. 1937
Investigations of the duration of the prepatent period and of the early clinical course of falciparum malaria (McLendon strain) were conducted with 16 non-immune American Negro men. Eight of the men were glucose-6-phosphate dehydrogenase (G6PD)-deficient and 8 were not. The investigations did not disclose evidence supporting the hypothesis that G6PD deficiency confers a biologic advantage against falciparum malaria.