The Treatment of Pinworm Infection in a School for the Mentally Retarded

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  • Department of Pediatrics, Edward J. Meyer Memorial Hospital, and State University of New York at Buffalo, School of Medicine, Buffalo, New York
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Two hundred fifty-nine patients infected with Enterobius vermicularis, in a school for the mentally retarded, were treated with one or another of three anthelmintics. Piperasine citrate alone in a single 4-g dose cured 23.9%; piperasine phosphate combined with senna in a single dose, supplying 4 g of piperasine and the equivalent of 30 mg of sennosides A and B, cured 41%; and stilbasium iodide in a single dose of 3 mg/kg cured 76.3%.

The single-dose schedule of these three anthelmintics as employed in this study failed to eliminate all the worms of all ages and stages of development.

While side effects in mentally retarded populations are not as readily recognized as in a normal population, the only ill effect observed in this study was some looseness of stools in some of the patients treated with piperazine phosphate and senna.