Detection of a Plasmodium Berghei-Antibody Complex Formed in Vivo

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  • Department of Veterinary Pathology and Hygiene, and the Center for Zoonoses Research, College of Veterinary Medicine, University of Illinois, Urbana, Illinois
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Direct staining of Plasmodium berghei with fluorescein-labeled antiserum from infected rodents indicated that these animals are capable of producing an antibody against the parasite. A naturally occurring P. berghei-antibody complex was detected by exposing parasitized erythrocytes from infected mice to fluoresceinlabeled anti-mouse globulin.