Ethanol Extracts of Various Helminths in a Complement Fixation Test for Eosinophilic Lung (Tropical Eosinophilia)

Guillermo Pacheco Department of Tropical Medicine and Public Health, Tulane University School of Medicine, Departments of Parasitology and Medicine, University of Singapore, New Orleans, U.S.A.

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T. J. Danaraj Department of Tropical Medicine and Public Health, Tulane University School of Medicine, Departments of Parasitology and Medicine, University of Singapore, New Orleans, U.S.A.

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Summary

Sera taken fortnightly from fourteen patients with eosinophilic lung (tropical eosinophilia) were tested by complement fixation with ethanol extracts of Dirofilaria immitis, Ascaris lumbricoides, Toxocara canis, Gnathostoma procyonis, Fasciola gigantica and Dipylidium caninum. Initially, sera from ten patients had high antibody titers with each of the extracts while antibodies were not detected in sera from the other four; after treatment with diethylcarbamazine the high titers decreased. It is concluded that the reactions obtained with these various extracts do not indicate infection with any particular helminth.

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