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The Serological Reactions in a Case of Rift Valley Fever
L. N. Binn
L. N. Binn
Department of Hazardous Operations, Walter Reed Army Institute of Research, Department of Medicine, School of Medicine, University of Maryland, Washington 12, D. C.
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Raymond Randall
Raymond Randall
Department of Hazardous Operations, Walter Reed Army Institute of Research, Department of Medicine, School of Medicine, University of Maryland, Washington 12, D. C.
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V. R. Harrison
V. R. Harrison
Department of Hazardous Operations, Walter Reed Army Institute of Research, Department of Medicine, School of Medicine, University of Maryland, Washington 12, D. C.
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C. J. Gibbs Jr.
C. J. Gibbs Jr.
Department of Hazardous Operations, Walter Reed Army Institute of Research, Department of Medicine, School of Medicine, University of Maryland, Washington 12, D. C.
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C. G. Aulisio
C. G. Aulisio
Department of Hazardous Operations, Walter Reed Army Institute of Research, Department of Medicine, School of Medicine, University of Maryland, Washington 12, D. C.
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Summary
The neutralizing (N), hemagglutination-inhibition (HI), and complement-fixation (CF) antibody responses following a laboratory infection with Rift Valley fever (RVF) virus in an individual have been determined. Neutralizing, HI, and CF antibodies persisted for the 18-month period of observation for which the individual was available. The advantages in economy and time required to perform HI and CF tests over the N test would be of particular value where serological cross-reactions do not occur, for example RVF.
Following inoculation of 2 cynomolgus monkeys with 106 mouse LD50 of pantropic RVF virus, the persistence of N, HI, and CF antibodies was observed for a 4-month period.
Author Notes
Present address: National Institutes of Health, Public Health Service, Department of Health, Education and Welfare, Bethesda, Maryland.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 505 | 231 | 8 |
| Full Text Views | 5 | 2 | 0 |
| PDF Downloads | 4 | 3 | 0 |