Grabar S, Costagliola D, 2021. Epidemiology of Kaposi’s sarcoma. Cancers 13: 5692.
Cesarman E, Damania B, Krown SE, Martin J, Bower M, Whitby D, 2019. Kaposi sarcoma. Nat Rev Dis Primers 5: 9.
eMedicine. Ophthalmologic Manifestations of Kaposi Sarcoma. Available at: https://emedicine.medscape.com/article/1197815-overview. Accessed August 20, 2024.
Yeak J, Iqbal T, Zahari M, Ismail F, 2019. Total resolution of ocular Kaposi sarcoma with different treatment approaches – A case series and review of literature. Int J STD AIDS 30: 802–809.
Bavishi A, Ashraf A, Lee L, 2012. AIDS-associated Kaposi’s sarcoma of the conjunctiva in a woman. Int J STD AIDS 23: 221–222.
Stebbing J, Portsmouth S, Gazzard B, 2003. How does HAART lead to the resolution of Kaposi’s sarcoma? J Antimicrob Chemother 51: 1095–1098.
Dupont C, Vasseur E, Beauchet A, Aegerter P, Berthé H, de Truchis P, Zucman D, Rouveix E, Saiag P, 2000. Long-term efficacy on Kaposi’s sarcoma of highly active antiretroviral therapy in a cohort of HIV-positive patients. CISIH 92. Centre d’information et de soins de l’immunodéficience humaine. AIDS 14: 987–993.
Mowatt L, 2013. Ophthalmic manifestations of HIV in the highly active anti-retroviral therapy era. West Indian Med J 62: 305–312.
Venkateswaran N, Ramos JC, Cohen AK, Alvarez OP, Cohen NK, Galor A, Karp CL, 2021. Spotlight on ocular Kaposi’s sarcoma: An update on the presentation, diagnosis, and management options. Expert Rev Ophthalmol 16: 477–489.
Dugel PU, Gill PS, Frangieh GT, Rao NA, 1990. Ocular adnexal Kaposi’s sarcoma in acquired immunodeficiency syndrome. Am J Ophthalmol 110: 500–503.
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Kaposi sarcoma is a low-grade vascular neoplasm linked to the human herpesvirus 8, with the AIDS-associated epidemic variant being the most common and aggressive. Although Kaposi sarcoma more commonly affects the cutaneous tissues, lymph nodes, and visceral organs, it can also be present in ocular and ocular adnexal tissues. We report a case of a 58-year-old Indo-Caribbean woman living with AIDS who presented with a large upper eyelid mass that was clinically diagnosed as Kaposi sarcoma. After the recommencement of the patient’s highly active antiretroviral therapy (HAART), the lesion showed marked regression, highlighting the critical role of HAART in the management of Kaposi sarcoma. This is the first documented case of AIDS-associated ocular Kaposi sarcoma in the Eastern Caribbean region and underscores the need to consider Kaposi sarcoma as a differential diagnosis in patients living with HIV/AIDS who present with ocular or ocular adnexal masses.
Current contact information: Cheyanne Francis, Department of Ophthalmology, Faculty of Medical Sciences, The University of The West Indies, St. Michael, Barbados, E-mail: cheyanne.francis@mycavehill.uwi.edu. Kirsten Da Silva, University of California San Francisco, San Francisco, CA, E-mail: kirsten.dasilva@ucsf.edu. Dawn Grosvenor, Faculty of Medical Sciences, The University of The West Indies, St. Michael, Barbados, E-mail: dawn.grosvenor@cavehill.uwi.edu.
Grabar S, Costagliola D, 2021. Epidemiology of Kaposi’s sarcoma. Cancers 13: 5692.
Cesarman E, Damania B, Krown SE, Martin J, Bower M, Whitby D, 2019. Kaposi sarcoma. Nat Rev Dis Primers 5: 9.
eMedicine. Ophthalmologic Manifestations of Kaposi Sarcoma. Available at: https://emedicine.medscape.com/article/1197815-overview. Accessed August 20, 2024.
Yeak J, Iqbal T, Zahari M, Ismail F, 2019. Total resolution of ocular Kaposi sarcoma with different treatment approaches – A case series and review of literature. Int J STD AIDS 30: 802–809.
Bavishi A, Ashraf A, Lee L, 2012. AIDS-associated Kaposi’s sarcoma of the conjunctiva in a woman. Int J STD AIDS 23: 221–222.
Stebbing J, Portsmouth S, Gazzard B, 2003. How does HAART lead to the resolution of Kaposi’s sarcoma? J Antimicrob Chemother 51: 1095–1098.
Dupont C, Vasseur E, Beauchet A, Aegerter P, Berthé H, de Truchis P, Zucman D, Rouveix E, Saiag P, 2000. Long-term efficacy on Kaposi’s sarcoma of highly active antiretroviral therapy in a cohort of HIV-positive patients. CISIH 92. Centre d’information et de soins de l’immunodéficience humaine. AIDS 14: 987–993.
Mowatt L, 2013. Ophthalmic manifestations of HIV in the highly active anti-retroviral therapy era. West Indian Med J 62: 305–312.
Venkateswaran N, Ramos JC, Cohen AK, Alvarez OP, Cohen NK, Galor A, Karp CL, 2021. Spotlight on ocular Kaposi’s sarcoma: An update on the presentation, diagnosis, and management options. Expert Rev Ophthalmol 16: 477–489.
Dugel PU, Gill PS, Frangieh GT, Rao NA, 1990. Ocular adnexal Kaposi’s sarcoma in acquired immunodeficiency syndrome. Am J Ophthalmol 110: 500–503.
Past two years | Past Year | Past 30 Days | |
---|---|---|---|
Abstract Views | 492 | 492 | 151 |
Full Text Views | 26 | 26 | 13 |
PDF Downloads | 26 | 26 | 10 |