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1.
Centers for Disease Control and Prevention, 2023. Measles (Rubeola). Available at: https://www.cdc.gov/measles/index.html. Accessed December 8, 2023.
-
2.
Centers for Disease Control and Prevention, 2023. Epidemiology and Prevention of Vaccine-Preventable Diseases. Available at: https://www.cdc.gov/pinkbook/hcp/table-of-contents/index.html?CDC_AAref_Val=https://www.cdc.gov/vaccines/pubs/pinkbook/downloads/meas.pdf. Accessed December 8, 2023.
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3.
World Health Organization, 2023. Measles. Available at: https://www.who.int/news-room/fact-sheets/detail/measles. Accessed December 8, 2023.
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4.
Lee K-Y, Lee H-S, Hur J-K, Kang J-H, Lee B-C, 2005. Clinical features of measles according to age in a measles epidemic. Scand J Infect Dis 37: 471–475.
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5.
Aritonovic Pribakovic J, Katanic N, Ilic A, Stojanovic Tasic M, Mitic NR, Mirkovic M, Radomirovic D, Milentijevic M, Mirkovic M, Katanic R, 2022. The measles epidemic in northern Kosovo and Metohija, Serbia, October 2017−August 2019. J Infect Dev Ctries 16: 850–856.
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6.
Sindhu TG, Geeta MG, Krishnakumar P, Sabitha S, Ajina KK, 2019. Clinical profile of measles in children with special reference to infants. Trop Doct 49: 20–23.
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7.
Zhao L, Wang Y, Chen X, Yang L, Cai M, Zhang Z, Zhang Y, Ma Y, 2023. Clinical characteristics of adult inpatients with Measles in Beijing from 2010 to 2021: A retrospective analysis. BMC Infect Dis 23: 312.
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8.
Gomber S, Arora SK, Das S, Ramachandran VG, 2011. Immune response to second dose of MMR vaccine in Indian children. Indian J Med Res 134: 302–306.
-
9.
Monsel G, Rapp C, Duong TA, Farhi D, Bouaziz JD, Meyssonnier V, Mirkamali A, Jaureguiberry S, Caumes E, 2011. Measles in adults: An emerging disease not sparing medical staff. Ann Dermatol Venereol 138: 107–110.
-
10.
Bianchi FP, Mascipinto S, Stefanizzi P, De Nitto S, Germinario C, Tafuri S, 2021. Long-term immunogenicity after measles vaccine vs. wild infection: An Italian retrospective cohort study. Hum Vaccin Immunother 17: 2078–2084.
-
11.
Anichini G, Gandolfo C, Fabrizi S, Miceli GB, Terrosi C, Gori Savellini G, Prathyumnan S, Orsi D, Battista G, Cusi MG, 2020. Seroprevalence to measles virus after vaccination or natural infection in an adult population, in Italy. Vaccines (Basel) 8: 66.
-
12.
Bianchi FP, Stefanizzi P, De Nitto S, Larocca AMV, Germinario C, Tafuri S, 2020. Long-term immunogenicity of measles vaccine: An Italian retrospective cohort study. J Infect Dis 221: 721–728.
-
13.
Ma C, Yan S, Su Q, Hao L, Tang S, An Z, He Y, Fan G, Rodewald L, Wang H, 2016. Measles transmission among adults with spread to children during an outbreak: Implications for measles elimination in China, 2014. Vaccine 34: 6539–6544.
-
14.
Association of Physicians of India, 2024. Indian Consensus Guideline on Adult Immunization. Available at: https://www.apiindia.org/reader/Indian%20Consensus%20Guideline%20on%20Adult%20Immunization. Accessed July 24, 2024.
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Ministry of Health & Family Welfare, Government of India, 2022. Roadmap to Measles and Rubella Elimination in India by 2023. New Delhi, India: Ministry of Health & Family Welfare, Government of India.
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A Case Series of Adult Measles from a Tertiary Care Hospital in North India
Suresh Selvam
Suresh Selvam
Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India;
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Deba Prasad Dhibar
Deba Prasad Dhibar
Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India;
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Harpreet Singh
hs.30.singh@gmail.com
Harpreet Singh
Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India;
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Vikas Suri
Vikas Suri
Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India;
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Vanita Sharma
Vanita Sharma
Department of Virology, Post Graduate Institute of Medical Education and Research, Chandigarh, India;
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Kapil Goyal
Kapil Goyal
Department of Virology, Post Graduate Institute of Medical Education and Research, Chandigarh, India;
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Srinivasan Selvamani
Srinivasan Selvamani
World Health Organization Office, New Delhi, India
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Mini P. Singh
Mini P. Singh
Department of Virology, Post Graduate Institute of Medical Education and Research, Chandigarh, India;
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Ashish Bhalla
Ashish Bhalla
Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India;
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ABSTRACT.
Measles or rubeola is caused by an enveloped single-stranded RNA virus belonging to the genus Morbillivirus in the Paramyxoviridae family. Here, we present five adult measles patients. The laboratory confirmation of measles by serology/polymerase chain reaction (PCR) was carried out in the National Measles Laboratory as per WHO standard operating procedure at the Department of Virology, Post Graduate Institute of Medical Education and Research, Chandigarh, India. All of the patients presented with prodromal fever with rash. Diffuse erythematous maculopapular rash in a centrifugal manner was present. Measles was diagnosed based on clinical examination findings and positive serology or PCR reports from throat swab specimens. Two patients had a history of exposure; other patients denied any exposure. All of the patients were admitted and managed conservatively in the isolation ward during the period of infectivity.
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Author Notes
Current contact information: Suresh Selvam, Deba Prasad Dhibhar, Harpreet Singh, Vikas Suri, and Ashish Bhalla, Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India, E-mails: sureshselvam92@gmail.com, drdebar_prasad@yahoo.co.in, hs.30.singh@gmail.com, surivikas9479@gmail.com, and bhalla.chd@gmail.com. Vanita Sharma, Kapil Goyal, and Mini P. Singh, Department of Virology, Post Graduate Institute of Medical Education and Research, Chandigarh, India, E-mails: vanitasharma91@gmail.com, kapilgoyalpgi@gmail.com, and minipsingh@gmail.com. Srinivasan Selvamani, World Health Organization Office, New Delhi, India, E-mail: dr.srinivasan.selvamani@gmail.com.
ProCite
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Reference Manager
BibTeX
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-
1.
Centers for Disease Control and Prevention, 2023. Measles (Rubeola). Available at: https://www.cdc.gov/measles/index.html. Accessed December 8, 2023.
-
2.
Centers for Disease Control and Prevention, 2023. Epidemiology and Prevention of Vaccine-Preventable Diseases. Available at: https://www.cdc.gov/pinkbook/hcp/table-of-contents/index.html?CDC_AAref_Val=https://www.cdc.gov/vaccines/pubs/pinkbook/downloads/meas.pdf. Accessed December 8, 2023.
-
3.
World Health Organization, 2023. Measles. Available at: https://www.who.int/news-room/fact-sheets/detail/measles. Accessed December 8, 2023.
-
4.
Lee K-Y, Lee H-S, Hur J-K, Kang J-H, Lee B-C, 2005. Clinical features of measles according to age in a measles epidemic. Scand J Infect Dis 37: 471–475.
-
5.
Aritonovic Pribakovic J, Katanic N, Ilic A, Stojanovic Tasic M, Mitic NR, Mirkovic M, Radomirovic D, Milentijevic M, Mirkovic M, Katanic R, 2022. The measles epidemic in northern Kosovo and Metohija, Serbia, October 2017−August 2019. J Infect Dev Ctries 16: 850–856.
-
6.
Sindhu TG, Geeta MG, Krishnakumar P, Sabitha S, Ajina KK, 2019. Clinical profile of measles in children with special reference to infants. Trop Doct 49: 20–23.
-
7.
Zhao L, Wang Y, Chen X, Yang L, Cai M, Zhang Z, Zhang Y, Ma Y, 2023. Clinical characteristics of adult inpatients with Measles in Beijing from 2010 to 2021: A retrospective analysis. BMC Infect Dis 23: 312.
-
8.
Gomber S, Arora SK, Das S, Ramachandran VG, 2011. Immune response to second dose of MMR vaccine in Indian children. Indian J Med Res 134: 302–306.
-
9.
Monsel G, Rapp C, Duong TA, Farhi D, Bouaziz JD, Meyssonnier V, Mirkamali A, Jaureguiberry S, Caumes E, 2011. Measles in adults: An emerging disease not sparing medical staff. Ann Dermatol Venereol 138: 107–110.
-
10.
Bianchi FP, Mascipinto S, Stefanizzi P, De Nitto S, Germinario C, Tafuri S, 2021. Long-term immunogenicity after measles vaccine vs. wild infection: An Italian retrospective cohort study. Hum Vaccin Immunother 17: 2078–2084.
-
11.
Anichini G, Gandolfo C, Fabrizi S, Miceli GB, Terrosi C, Gori Savellini G, Prathyumnan S, Orsi D, Battista G, Cusi MG, 2020. Seroprevalence to measles virus after vaccination or natural infection in an adult population, in Italy. Vaccines (Basel) 8: 66.
-
12.
Bianchi FP, Stefanizzi P, De Nitto S, Larocca AMV, Germinario C, Tafuri S, 2020. Long-term immunogenicity of measles vaccine: An Italian retrospective cohort study. J Infect Dis 221: 721–728.
-
13.
Ma C, Yan S, Su Q, Hao L, Tang S, An Z, He Y, Fan G, Rodewald L, Wang H, 2016. Measles transmission among adults with spread to children during an outbreak: Implications for measles elimination in China, 2014. Vaccine 34: 6539–6544.
-
14.
Association of Physicians of India, 2024. Indian Consensus Guideline on Adult Immunization. Available at: https://www.apiindia.org/reader/Indian%20Consensus%20Guideline%20on%20Adult%20Immunization. Accessed July 24, 2024.
-
15.
Ministry of Health & Family Welfare, Government of India, 2022. Roadmap to Measles and Rubella Elimination in India by 2023. New Delhi, India: Ministry of Health & Family Welfare, Government of India.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1138 | 1138 | 555 |
| Full Text Views | 22 | 22 | 13 |
| PDF Downloads | 24 | 24 | 14 |