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Mukuku O, Sánchez SS, Bugeme M, Garcia HH, 2020. Case report: Three cases of neurocysticercosis in Central Africa.Am J Trop Med Hyg 103: 1955–1957.
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Exploring Geophagy as a Risk Factor for Neurocysticercosis: A Case Series from the Democratic Republic of the Congo
Olivier Mukuku
oliviermukuku@yahoo.fr
Olivier Mukuku
Department of Research, Institut Supérieur des Techniques Médicales de Lubumbashi, Lubumbashi, Democratic Republic of the Congo;
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Sofía S. Sánchez
Sofía S. Sánchez
Cysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Peru;
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Marcellin Bugeme
Marcellin Bugeme
Department of Neuropsychiatric, University of Lubumbashi, Lubumbashi, Democratic Republic of the Congo;
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Hector H. Garcia
Hector H. Garcia
Cysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Peru;
Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru
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Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru
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ABSTRACT.
Neurocysticercosis (NCC) is a common parasitic neuroinfectious disease caused by humans becoming intermediate hosts in the life cycle of the pig tapeworm, Taenia solium, after ingesting its eggs. This case series examines seven female patients with NCC who engaged in geophagy (soil consumption) and were evaluated at Centre Médical Baraka in Lubumbashi, Democratic Republic of the Congo, from January 2019 to December 2020. From a cohort of 176 patients with epilepsy evaluated during that period, 105 underwent brain computed tomography scans, and 36 were confirmed to have NCC. Among those with NCC, seven (19.4%) had a history of geophagy and were included in this case series. The majority of these patients had more than five brain lesions. Neuroimaging revealed colloidal lesions, third-stage lesions, and calcifications in six patients. All patients showed improvement after treatment with antiseizure medication alone or in combination with antiparasitic drugs. Geophagy, although not common, serves as a mode of contamination in which individuals ingest soil containing Taenia eggs, potentially leading to the development of NCC.
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Author Notes
Current contact information: Olivier Mukuku, Institut Supérieur des Techniques Médicales de Lubumbashi, Lubumbashi, Democratic Republic of the Congo, E-mail: oliviermukuku@yahoo.fr. Sofía S. Sánchez, Cysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Peru, E-mail: sssboluarte@gmail.com. Marcellin Bugeme, University of Lubumbashi, Lubumbashi, Democratic Republic of the Congo, E-mail: marcellinbugeme@yahoo.fr. Hector H. Garcia, Cysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Peru, and Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru, E-mail: hgarcia@jhsph.edu.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
World Health Organization, 2003. Control of Neucysticercosis: Report of the Secretariat (No. A56/10). Geneva, Switzerland: WHO.
-
2.
Lescano AG, Garcia HH, Gilman RH, Gavidia CM, Tsang VCW, Rodriguez S, Moulton LH, Villaran MV, Montano SM, Gonzalez AE; Cysticercosis Working Group in Peru, 2009. Taenia solium cysticercosis hotspots surrounding tapeworm carriers: Clustering on human seroprevalence but not on seizures. PLoS Negl Trop Dis 3: e371.
-
3.
Garcia HH, Nash TE, Del Brutto OH, 2014. Clinical symptoms, diagnosis, and treatment of neurocysticercosis. Lancet Neurol 13: 1202–1215.
-
4.
DSM-5 Task Force, 2013. Diagnostic and Statistical Manual of Mental Disorders: DSM-5. 5th ed. Arlington, VA: American Psychiatric Association.
-
5.
Carabin H, Ndimubanzi PC, Budke CM, Nguyen H, Qian Y, Cowan LD, Stoner JA, Rainwater E, Dickey M, 2011. Clinical manifestations associated with neurocysticercosis: A systematic review. PLoS Negl Trop Dis 5: e1152.
-
6.
Bouteille B, 2014. Epidemiology of cysticercosis and neurocysticercosis.Med Sante Trop 24: 367–374.
-
7.
Zafindraibe NJ, Ralalarinivo J, Rakotoniaina AI, Maeder MN, Andrianarivelo MR, Contamin B, Michault A, Rasamindrakotroka A, 2017. Seroprevalence of cysticercosis and associated risk factors in a group of patients seen at the Centre Hospitalier Régional de Référence d’Antsirabe, Madagascar. Pan Afr Med J 28: 260.
-
8.
Wong MS, Bundy DA, Golden MH, 1988. Quantitative assessment of geophagous behaviour as a potential source of exposure to geohelminth infection.Trans R Soc Trop Med Hyg 82: 621–625.
-
9.
Sahai S, Sahai A, 2013. Pica causing neurocysticercosis in pregnancy presenting as eclampsia: A report of two cases. J Obstet Gynaecol India 63: 68–69.
-
10.
Huerta M et al., 2008. Parasite contamination of soil in households of a Mexican rural community endemic for neurocysticercosis.Trans R Soc Trop Med Hyg 102: 374–379.
-
11.
Millogo A et al., 2012. Prevalence of neurocysticercosis among people with epilepsy in rural areas of Burkina Faso. Epilepsia 53: 2194–2202.
-
12.
Bugeme M, Sow AD, Mukuku O, Millogo A, Luboya O, Touré K, 2020. Epilepsy due to neurocysticercosis: Analysis of a hospital cohort. J Neurosci Neurol Disord 4: 63–68.
-
13.
Mukuku O, Sánchez SS, Bugeme M, Garcia HH, 2020. Case report: Three cases of neurocysticercosis in Central Africa.Am J Trop Med Hyg 103: 1955–1957.
-
14.
Webb CM, White AC, 2016. Update on the diagnosis and management of neurocysticercosis.Curr Infect Dis Rep 18: 44.
-
15.
Del Brutto OH et al., 2001. Proposed diagnostic criteria for neurocysticercosis. Neurology 57: 177–183.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1918 | 1918 | 406 |
| Full Text Views | 51 | 51 | 2 |
| PDF Downloads | 65 | 65 | 3 |