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-
1.
Prabhu RM, Patel R, 2004. Mucormycosis and entomophthoramycosis: A review of the clinical manifestations, diagnosis and treatment. Clin Microbiol Infect 10: 31–47.
-
2.
Chappity P, Hallur V, 2021. Subcutaneous fungal infection of the face. Lancet Infect Dis 21: 296.
-
3.
Varghese L, et al., 2021. Rhinofacial conidiobolomycosis: Clinical and microbiological characterisation and shift in the management of a rare disease. Mycoses 64: 882–889.
-
4.
Gupta P, Pilania RK, Kaur H, Rudramurthy SM, Soni R, Batra N, Verma R, Singh S, Chatterjee D, 2022. Pediatric case of conidiobolomycosis: A rare entity. Pediatr Dermatol 39: 149–150.
-
5.
Nathan MD, Keller AP Jr, Lerner CJ, Davis JC, 1982. Entomophthorales infection of the maxillofacial region. Laryngoscope 92: 767–769.
-
6.
Stavropoulou E, Coste AT, Beigelman-Aubry C, Letovanec I, Spertini O, Lovis A, Krueger T, Burger R, Bochud PY, Lamoth F, 2020. Conidiobolus pachyzygosporus invasive pulmonary infection in a patient with acute myeloid leukemia: Case report and review of the literature. BMC Infect Dis 20: 527.
-
7.
Wüppenhorst N, Lee M-K, Rappold E, Kayser G, Beckervordersandforth J, de With K, Serr A, 2010. Rhino-orbitocerebral zygomycosis caused by Conidiobolus incongruus in an immunocompromised patient in Germany. J Clin Microbiol 48: 4322–4325.
-
8.
Kimura M, Yaguchi T, Sutton DA, Fothergill AW, Thompson EH, Wickes BL, 2011. Disseminated human conidiobolomycosis due to Conidiobolus lamprauges. J Clin Microbiol 49: 752–756.
-
9.
Sigera LSM, Janappriya GHDC, Lakshan MTD, Pitigalage NJ, Jayasekera PI, Dayasena RP, Patabendige CGUA, Gunasekera CN, 2021. Rhinofacial conidiobolomycosis: A case series and review of the literature. Ear Nose Throat J 100 (Suppl ):835S–841S.
-
10.
Varshney S, Gupta P, Bist SS, Bhagat S, 2015. Conidiobolus coronatus granuloma of the right inferior turbinate: A rare presentation. Ear Nose Throat J 94: E32–E35.
-
11.
Pujary P, Pujary K, Mahesh SG, Valiathan M, 2008. Conidiobolus coronata granuloma of left inferior turbinate: A rare presentation. J Laryngol Otol 122: e15.
-
12.
Purohit G, Sable M, Rudramurthy SM, Sarkar S, Parida P, Deshmukh V, Hallur V, 2021. A rare case of condiobolomycosis due to Conidiobolus coronatus presenting with dysphagia. Indian J Med Microbiol 39: 558–560.
-
13.
Thomas MM, Bai MS, Jayaprakash C, Jose P, Ebenezer R, 2006. Rhinoentomophthoromycosis. Indian J Dermatol Venereol 72: 296–299.
-
14.
Chadaram S, Chappity P, Hallur V, Sharma P, Pradeep P, Parida P, 2022. Efficacy of two-phase treatment regimen for rhino-facial entomophthoromycosis: Our experience and review of literature. Oman Med J 37: e448.
-
15.
Yu WN, Chen CJ, Chen CM, 2014. Pharyngeal entomophthoromycosis. J Chin Med Assoc 77: 337–340.
-
16.
Deak L, Mudalagiriyappa S, Ballin A, Saxton D, Chakrabarti A, 2018. A rhinofacial Conidiobolus coronatus fungal infection presenting as an intranasal tumour. Sultan Qaboos Univ Med J 18: e549–e552.
-
17.
Guarro J, Aguilar C, Pujol I, 1999. In-vitro antifungal susceptibilities of Basidiobolus and Conidiobolus spp. strains. J Antimicrob Chemother 44: 557–560.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 256 | 256 | 69 |
| Full Text Views | 14 | 14 | 4 |
| PDF Downloads | 23 | 23 | 6 |
Successful Management of Rhinofacial Conidiobolus coronatus Infection with Itraconazole Monotherapy
Savitha Sharath
Savitha Sharath
Department of Dermatology, Venereology and Leprosy, Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital, New Delhi, India;
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Abhinav Bansal
Abhinav Bansal
Department of Dermatology, Venereology and Leprosy, Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital, New Delhi, India;
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Surabhi Sinha
surabhi2310@gmail.com
Surabhi Sinha
Department of Dermatology, Venereology and Leprosy, Lady Harding Medical College, New Delhi, India;
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Arvind Ahuja
Arvind Ahuja
Department of Pathology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital, New Delhi, India
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ABSTRACT.
There are no standard guidelines on the management of Conidiobolus infections, and many antifungals have been used, either alone or in combination. Relapses are common even after successful management. Although localized, they can result in severe facial disfigurement and may rarely cause disseminated entomophthoromycosis, which can have fatal complications. We present a case of biopsy-proven conidiobolomycosis in a young immunocompetent male patient with progressive unilateral rhinofacial swelling who was successfully treated with itraconazole monotherapy and showed no relapse after 1 year of therapy.
Author Notes
Current contact information: Savitha Sharath, Abhinav Bansal, and Arvind Ahuja, Department of Dermatology, Venereology and Leprosy, Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital, New Delhi, India, E-mails: savitharavivarma@gmail.com, abhinavbansal866@gmail.com, and drarvindahuja@gmail.com. Surabhi Sinha, Department of Dermatology, Venereology and Leprosy, Lady Hardinge Medical College, New Delhi, India, E-mail: surabhi2610@gmail.com.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Prabhu RM, Patel R, 2004. Mucormycosis and entomophthoramycosis: A review of the clinical manifestations, diagnosis and treatment. Clin Microbiol Infect 10: 31–47.
-
2.
Chappity P, Hallur V, 2021. Subcutaneous fungal infection of the face. Lancet Infect Dis 21: 296.
-
3.
Varghese L, et al., 2021. Rhinofacial conidiobolomycosis: Clinical and microbiological characterisation and shift in the management of a rare disease. Mycoses 64: 882–889.
-
4.
Gupta P, Pilania RK, Kaur H, Rudramurthy SM, Soni R, Batra N, Verma R, Singh S, Chatterjee D, 2022. Pediatric case of conidiobolomycosis: A rare entity. Pediatr Dermatol 39: 149–150.
-
5.
Nathan MD, Keller AP Jr, Lerner CJ, Davis JC, 1982. Entomophthorales infection of the maxillofacial region. Laryngoscope 92: 767–769.
-
6.
Stavropoulou E, Coste AT, Beigelman-Aubry C, Letovanec I, Spertini O, Lovis A, Krueger T, Burger R, Bochud PY, Lamoth F, 2020. Conidiobolus pachyzygosporus invasive pulmonary infection in a patient with acute myeloid leukemia: Case report and review of the literature. BMC Infect Dis 20: 527.
-
7.
Wüppenhorst N, Lee M-K, Rappold E, Kayser G, Beckervordersandforth J, de With K, Serr A, 2010. Rhino-orbitocerebral zygomycosis caused by Conidiobolus incongruus in an immunocompromised patient in Germany. J Clin Microbiol 48: 4322–4325.
-
8.
Kimura M, Yaguchi T, Sutton DA, Fothergill AW, Thompson EH, Wickes BL, 2011. Disseminated human conidiobolomycosis due to Conidiobolus lamprauges. J Clin Microbiol 49: 752–756.
-
9.
Sigera LSM, Janappriya GHDC, Lakshan MTD, Pitigalage NJ, Jayasekera PI, Dayasena RP, Patabendige CGUA, Gunasekera CN, 2021. Rhinofacial conidiobolomycosis: A case series and review of the literature. Ear Nose Throat J 100 (Suppl ):835S–841S.
-
10.
Varshney S, Gupta P, Bist SS, Bhagat S, 2015. Conidiobolus coronatus granuloma of the right inferior turbinate: A rare presentation. Ear Nose Throat J 94: E32–E35.
-
11.
Pujary P, Pujary K, Mahesh SG, Valiathan M, 2008. Conidiobolus coronata granuloma of left inferior turbinate: A rare presentation. J Laryngol Otol 122: e15.
-
12.
Purohit G, Sable M, Rudramurthy SM, Sarkar S, Parida P, Deshmukh V, Hallur V, 2021. A rare case of condiobolomycosis due to Conidiobolus coronatus presenting with dysphagia. Indian J Med Microbiol 39: 558–560.
-
13.
Thomas MM, Bai MS, Jayaprakash C, Jose P, Ebenezer R, 2006. Rhinoentomophthoromycosis. Indian J Dermatol Venereol 72: 296–299.
-
14.
Chadaram S, Chappity P, Hallur V, Sharma P, Pradeep P, Parida P, 2022. Efficacy of two-phase treatment regimen for rhino-facial entomophthoromycosis: Our experience and review of literature. Oman Med J 37: e448.
-
15.
Yu WN, Chen CJ, Chen CM, 2014. Pharyngeal entomophthoromycosis. J Chin Med Assoc 77: 337–340.
-
16.
Deak L, Mudalagiriyappa S, Ballin A, Saxton D, Chakrabarti A, 2018. A rhinofacial Conidiobolus coronatus fungal infection presenting as an intranasal tumour. Sultan Qaboos Univ Med J 18: e549–e552.
-
17.
Guarro J, Aguilar C, Pujol I, 1999. In-vitro antifungal susceptibilities of Basidiobolus and Conidiobolus spp. strains. J Antimicrob Chemother 44: 557–560.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 256 | 256 | 69 |
| Full Text Views | 14 | 14 | 4 |
| PDF Downloads | 23 | 23 | 6 |