ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
WHO and IAEA , 2020. Guidance Framework for Testing the Sterile Insect Technique as a Vector Control Tool against Aedes-Borne diseases. License: CC BY-NC SA 3.0 IGO. Geneva, Switzerland: World Health Organization and the International Atomic Energy Agency.
-
2.
Oliva CF et al., 2021. Sterile insect technique (SIT) against Aedes species mosquitoes: A roadmap and good practice framework for designing, implementing and evaluating pilot field trials. Insects 12: 191.
-
3.
Aldridge RL , Kline J , Coburn JM , Britch SC , Boardman L , Hahn DA , Chen C , Linthicum KJ , 2020. Gamma-irradiation reduces survivorship, feeding behavior, and oviposition of female Aedes aegypti. J Am Mosq Control Assoc 36: 152–160.
-
4.
Kittayapong P , Ninphanomchai S , Limohpasmanee W , Chansang C , Chansang U , Mongkalangoon P , 2019. Combined sterile insect technique and incompatible insect technique: The first proof-of-concept to suppress Aedes aegypti vector populations in semi-rural settings in Thailand. PLoS Negl Trop Dis 13: e0007771.
-
5.
Gato R et al., 2021. Sterile insect technique: Successful suppression of an Aedes aegypti field population in Cuba. Insects 12: 469.
-
6.
Marina CF , Liedo P , Bond JGR , Osorio A , Valle J , Angulo-Kladt R , Gómez-Simuta Y , Fernández-Salas I , Dor A , Williams T , 2022. Comparison of ground release and drone-mediated aerial release of Aedes aegypti sterile males in southern Mexico: Efficacy and challenges. Insects 13: 347.
-
7.
Dame DA , Benedict MQ , Robinson AS , Knols BGJ , 2009. Historical applications of induced sterilisation in field populations of mosquitoes. Malar J 8: S2.
-
8.
Zheng X et al., 2019. Incompatible and sterile insect techniques combined eliminate mosquitoes. Nature 572: 56–61.
-
9.
Cunningham CA , Aldridge RL , Kline J , Bibbs CS , Linthicum KJ , Xue RD , 2020. Effects of radiation on blood-feeding activity of Aedes aegypti (Diptera: Culicidae). J Vector Ecol 45: 135–136.
-
10.
Chen C , Aldridge RL , Gibson S , Kline J , Aryaprema V , Qualls W , Xue RD , Boardman L , Linthicum KJ , Hahn DA , 2022. Developing radiation‐based sterile insect technique (SIT) for controlling Aedes aegypti: Identification of a sterilizing dose. Pest Manag Sci 79: 1175–1183.
-
11.
Bourtzis K , Lees RS , Hendrichs J , Vreysen MJB , 2016. More than one rabbit out of the hat: Radiation, transgenic and symbiont-based approaches for sustainable management of mosquito and tsetse fly populations. Acta Trop 157: 115–130.
-
12.
Balestrino F , Bouyer J , Vreysen M , Veronesi E , 2022. Impact of irradiation on vector competence of Aedes aegypti and Aedes albopictus for dengue and chikungunya viruses. Front Bioeng Biotechnol 10: 876400.
-
13.
da Silva EB et al., 2023. Effects of gamma radiation on the vector competence of Aedes aegypti (Diptera: Culicidae) to transmit Zika virus. Acta Trop 239: 106831.
-
14.
Griffin DE , Weaver SC , Knipe DM , Howley PM & Whelan S Fields Virology, 7th ed. Philadelphia, PA: Lippincott Williams & Wilkins, 194–245.
-
15.
Anderson CR , Downs WG , Wattley GH , Ahin NW , Reese AA , 1957. Mayaro virus: A new human disease agent. II. Isolation from blood of patients in Trinidad, B.W.I. Am J Trop Med Hyg 6: 1012–1016.
-
16.
Hoch AL , Peterson NE , LeDuc JW , Pinheiro FP , 1981. An outbreak of Mayaro virus disease in Belterra, Brazil. III. Entomological and ecological studies. Am J Trop Med Hyg 30: 689–698.
-
17.
Causey OR , Maroja OM , 1957. Mayaro virus: A new human disease agent. III. Investigation of an epidemic of acute febrile illness on the River Guana in Para, Brazil, and isolation of Mayaro virus as causative agent. Am J Trop Med Hyg 6: 1017–1023.
-
18.
Karabatsos N , 1985. International Catalogue of Arboviruses Including Certain Other Viruses of Vertebrates. 3rd ed. San Antonio, TX: American Society of Tropical Medicine and Hygiene, 673–674.
-
19.
Metselaar D , 1966. Isolation of arboviruses of group A and group C in Suriname. Trop Geogr Med 18: 137–142.
-
20.
Talarmin A et al., 1998. Mayaro virus fever in French Guiana: Isolation, identification and seroprevalence. Am J Trop Med Hyg 59: 452–456.
-
21.
Pinheiro FP , Freitas RB , Travossos da Rosa JR , Gabbay YB , Mello WA , LeDuc JW , 1981. An outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings. Am J Trop Med Hyg 30: 674–681.
-
22.
Schaeffer M , Gajdusek DC , Lema AB , Eichenwald H , 1959. Epidemic jungle fevers among Okinawan colonists in the Bolivian rain forest. I. Epidemiology. Am J Trop Med Hyg 8: 372–396.
-
23.
Lednicky J et al., 2016. Mayaro virus in child with acute febrile illness, Haiti, 2015. Emerg Infect Dis 22: 2000–2002.
-
24.
Llagonne-Barets M , Icard V , Leparc-Goffart I , Prat C , Perpoint T , Andre P , Ramiere C , 2016. A case of Mayaro virus infection imported from French Guiana. J Clin Virol 77: 66–68.
-
25.
Santiago FW , Halsey ES , Siles C , Vilcarromero S , Guevara C , Silvas JA , Ramal C , Ampuero JS , Aguilar PV , 2015. Long-term arthralgia after Mayaro virus infection correlates with sustained pro-inflammatory cytokine response. PLoS Negl Trop Dis 9: e0004104.
-
26.
Vasconcelo PFC , Calisher CH , 2016. Emergence of human arboviral diseases in the Americas, 2000–2016. Vector Borne Zoonotic Dis 16: 295–301.
-
27.
Gerberg EJ , Barnard DR , Ward RA , 1994. Manual for Mosquito Rearing and Experimental Techniques. Sacramento, CA: American Mosquito Control Association, Inc.
-
28.
Moreno BJ , Aldridge RL , Britch SC , Bayer BE , Kline J , Hahn DA , Chen C , Linthicum KJ , 2021. Preparing irradiated and marked male Aedes aegypti mosquitoes for release in an operational sterile insect technique program. J Vis Exp 169, doi: 10.3791/62260.
-
29.
Crawford JE , Clarke DW , Criswell V , Desnoyer M , Cornel D , Deegan B , 2020. Efficient production of male Wolbachia-infected Aedes aegypti mosquitoes enables large-scale suppression of wild populations. Nat Biotechnol 38: 482–492.
-
30.
Turell MJ , Wilson WC , Bennett KE , 2010. Potential for North American mosquitoes (Diptera: Culicidae) to transmit Rift Valley fever virus. J Med Entomol 47: 884–889.
-
31.
Turell MJ , Britch SC , Aldridge RL , Kline DL , Boohene C , Linthicum KJ , 2013. Potential for mosquitoes (Diptera: Culicidae) from Florida to transmit Rift Valley fever virus. J Med Entomol 50: 1111–1117.
-
32.
Moutailler S , Krida G , Schaffner F , Vazeille M , Failloux A-B , 2008. Potential vectors of Rift Valley fever virus in the Mediterranean region. Vector Borne Zoonotic Dis 8: 749–753.
-
33.
Lumley S , Hernández-Triana LM , Horton DL , Fernández de Marco MDM , Medlock JM , Hewson R , Fooks AR , Johnson N , 2018. Competence of mosquitoes native to the United Kingdom to support replication and transmission of Rift Valley fever virus. Parasit Vectors 11: 308.
-
34.
Brustolin M et al., 2017. Rift Valley fever virus and European mosquitoes: Vector competence of Culex pipiens and Stegomyia albopicta (= Aedes albopictus). Med Vet Entomol 31: 365–372.
-
35.
Moretti R , Lampazzi E , Damiani C , Fabbri G , Lombardi G , Pioli C , Desiderio A , Serrao A , Calvitti M , 2022. Increased biting rate and decreased Wolbachia density in irradiated Aedes mosquitoes. Parasit Vectors 15: 67.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 422 | 422 | 77 |
| Full Text Views | 20 | 20 | 9 |
| PDF Downloads | 23 | 23 | 13 |
Gamma-Irradiated Female Aedes aegypti Mosquitoes Exhibit Greater Susceptibility to Mayaro Virus
Stephanie V. Trefry
Stephanie V. Trefry
Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland;
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Robert L. Aldridge
Robert L. Aldridge
Center for Medical, Agricultural, and Veterinary Entomology, Agricultural Research Service, United States Department of Agriculture, Gainesville, Florida;
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Thomas R. Sprague
Thomas R. Sprague
Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland;
BioFactura Inc., Frederick, Maryland;
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BioFactura Inc., Frederick, Maryland;
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Robert G. Lowen
Robert G. Lowen
Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland;
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Jesse H. Erasmus
Jesse H. Erasmus
Department of Microbiology, University of Washington, Seattle, Washington;
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Margaret L. Pitt
Margaret L. Pitt
Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland;
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Daniel A. Hahn
Daniel A. Hahn
Department of Entomology and Nematology, University of Florida, Gainesville, Florida
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Farooq Nasar
Farooq Nasar
Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland;
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Seth Gibson
Seth Gibson
Center for Medical, Agricultural, and Veterinary Entomology, Agricultural Research Service, United States Department of Agriculture, Gainesville, Florida;
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Kenneth J. Linthicum
Kenneth J. Linthicum
Center for Medical, Agricultural, and Veterinary Entomology, Agricultural Research Service, United States Department of Agriculture, Gainesville, Florida;
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ABSTRACT.
Mayaro virus (MAYV) is an alphavirus endemic in many parts of Central and South America transmitted to humans by Aedes aegypti. Currently, there is no vaccine or treatment of Mayaro infection, and therefore it is essential to control transmission by reducing populations of Ae. aegypti. Unfortunately, Ae. aegypti are extremely difficult to control with traditional integrated vector management (IVM) because of factors such as growing resistance to a dwindling list of registered insecticides and cryptic immature and adult habitats. The sterile insect technique (SIT) by irradiation is gaining traction as a novel supplemental tool to IVM. The SIT is being used operationally to release large numbers of sterilized colony-reared male mosquitoes in an intervention area to overwhelm females in the natural population, eventually causing population decline because of high frequencies of unfertilized eggs. However, little is known about the effect of irradiation on vector competence for mosquito-borne viruses such as MAYV in females that may be accidentally reared, irradiated, and released alongside males. In this investigation, we exposed female Ae. aegypti pupae to radiation and evaluated vector competence after inoculation with MAYV. Infection and dissemination rates of irradiated (10 and 40 Gy) Ae. aegypti were higher than those of non-irradiated cohorts at 7 and 14 days after infection. Although these results indicate a need to maintain effective sex sorting prior to irradiation and release of Ae. aegypti, our results are consistent with several previous observations that vectorial capacity and vector competence are likely lower in irradiated than in nonirradiated females.
Author Notes
Financial support: This study was supported by a grant from the
Disclosure: The views expressed in this article are those of the authors and do not reflect the official policy or position of the DoD, the Department of the Army, or the USDA.
Current contact information: Stephanie V. Trefry, Tonix Pharmaceuticals, Frederick, Maryland. E-mail: svaldez1@alumni.jh.edu. Robert L. Aldridge, Seth Gibson, and Kenneth J. Linthicum, Center for Medical, Agricultural, and Veterinary Entomology, Agricultural Research Service, United States Department of Agriculture, Gainesville, Florida. E-mails: robert.aldridge@usda.gov, seth.gibson@usda.gov, and linthicumken@aol.com. Thomas R. Sprague, BioFactura Inc., Frederick, Maryland. E-mail: thomassprague3@yahoo.com. Robert G. Lowen and Margaret L. Pitt, Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland. E-mails: third_cent@yahoo.com and margaret.l.pitt.civ@mail.mil. Jesse H. Erasmus, Department of Microbiology, University of Washington, Seattle, Washington. E-mail: Daniel A. Hahn, Department of Entomology and Nematology, University of Florida, Gainesville, Florida. E-mail: dahahn@ufl.edu. Farooq Nasar, Center for Medical, Agricultural, and Veterinary Entomology, Agricultural Research Service, United States Department of Agriculture, Gainesville, Florida and Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas. E-mail: fanasar@utmb.edu.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
WHO and IAEA , 2020. Guidance Framework for Testing the Sterile Insect Technique as a Vector Control Tool against Aedes-Borne diseases. License: CC BY-NC SA 3.0 IGO. Geneva, Switzerland: World Health Organization and the International Atomic Energy Agency.
-
2.
Oliva CF et al., 2021. Sterile insect technique (SIT) against Aedes species mosquitoes: A roadmap and good practice framework for designing, implementing and evaluating pilot field trials. Insects 12: 191.
-
3.
Aldridge RL , Kline J , Coburn JM , Britch SC , Boardman L , Hahn DA , Chen C , Linthicum KJ , 2020. Gamma-irradiation reduces survivorship, feeding behavior, and oviposition of female Aedes aegypti. J Am Mosq Control Assoc 36: 152–160.
-
4.
Kittayapong P , Ninphanomchai S , Limohpasmanee W , Chansang C , Chansang U , Mongkalangoon P , 2019. Combined sterile insect technique and incompatible insect technique: The first proof-of-concept to suppress Aedes aegypti vector populations in semi-rural settings in Thailand. PLoS Negl Trop Dis 13: e0007771.
-
5.
Gato R et al., 2021. Sterile insect technique: Successful suppression of an Aedes aegypti field population in Cuba. Insects 12: 469.
-
6.
Marina CF , Liedo P , Bond JGR , Osorio A , Valle J , Angulo-Kladt R , Gómez-Simuta Y , Fernández-Salas I , Dor A , Williams T , 2022. Comparison of ground release and drone-mediated aerial release of Aedes aegypti sterile males in southern Mexico: Efficacy and challenges. Insects 13: 347.
-
7.
Dame DA , Benedict MQ , Robinson AS , Knols BGJ , 2009. Historical applications of induced sterilisation in field populations of mosquitoes. Malar J 8: S2.
-
8.
Zheng X et al., 2019. Incompatible and sterile insect techniques combined eliminate mosquitoes. Nature 572: 56–61.
-
9.
Cunningham CA , Aldridge RL , Kline J , Bibbs CS , Linthicum KJ , Xue RD , 2020. Effects of radiation on blood-feeding activity of Aedes aegypti (Diptera: Culicidae). J Vector Ecol 45: 135–136.
-
10.
Chen C , Aldridge RL , Gibson S , Kline J , Aryaprema V , Qualls W , Xue RD , Boardman L , Linthicum KJ , Hahn DA , 2022. Developing radiation‐based sterile insect technique (SIT) for controlling Aedes aegypti: Identification of a sterilizing dose. Pest Manag Sci 79: 1175–1183.
-
11.
Bourtzis K , Lees RS , Hendrichs J , Vreysen MJB , 2016. More than one rabbit out of the hat: Radiation, transgenic and symbiont-based approaches for sustainable management of mosquito and tsetse fly populations. Acta Trop 157: 115–130.
-
12.
Balestrino F , Bouyer J , Vreysen M , Veronesi E , 2022. Impact of irradiation on vector competence of Aedes aegypti and Aedes albopictus for dengue and chikungunya viruses. Front Bioeng Biotechnol 10: 876400.
-
13.
da Silva EB et al., 2023. Effects of gamma radiation on the vector competence of Aedes aegypti (Diptera: Culicidae) to transmit Zika virus. Acta Trop 239: 106831.
-
14.
Griffin DE , Weaver SC , Knipe DM , Howley PM & Whelan S Fields Virology, 7th ed. Philadelphia, PA: Lippincott Williams & Wilkins, 194–245.
-
15.
Anderson CR , Downs WG , Wattley GH , Ahin NW , Reese AA , 1957. Mayaro virus: A new human disease agent. II. Isolation from blood of patients in Trinidad, B.W.I. Am J Trop Med Hyg 6: 1012–1016.
-
16.
Hoch AL , Peterson NE , LeDuc JW , Pinheiro FP , 1981. An outbreak of Mayaro virus disease in Belterra, Brazil. III. Entomological and ecological studies. Am J Trop Med Hyg 30: 689–698.
-
17.
Causey OR , Maroja OM , 1957. Mayaro virus: A new human disease agent. III. Investigation of an epidemic of acute febrile illness on the River Guana in Para, Brazil, and isolation of Mayaro virus as causative agent. Am J Trop Med Hyg 6: 1017–1023.
-
18.
Karabatsos N , 1985. International Catalogue of Arboviruses Including Certain Other Viruses of Vertebrates. 3rd ed. San Antonio, TX: American Society of Tropical Medicine and Hygiene, 673–674.
-
19.
Metselaar D , 1966. Isolation of arboviruses of group A and group C in Suriname. Trop Geogr Med 18: 137–142.
-
20.
Talarmin A et al., 1998. Mayaro virus fever in French Guiana: Isolation, identification and seroprevalence. Am J Trop Med Hyg 59: 452–456.
-
21.
Pinheiro FP , Freitas RB , Travossos da Rosa JR , Gabbay YB , Mello WA , LeDuc JW , 1981. An outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings. Am J Trop Med Hyg 30: 674–681.
-
22.
Schaeffer M , Gajdusek DC , Lema AB , Eichenwald H , 1959. Epidemic jungle fevers among Okinawan colonists in the Bolivian rain forest. I. Epidemiology. Am J Trop Med Hyg 8: 372–396.
-
23.
Lednicky J et al., 2016. Mayaro virus in child with acute febrile illness, Haiti, 2015. Emerg Infect Dis 22: 2000–2002.
-
24.
Llagonne-Barets M , Icard V , Leparc-Goffart I , Prat C , Perpoint T , Andre P , Ramiere C , 2016. A case of Mayaro virus infection imported from French Guiana. J Clin Virol 77: 66–68.
-
25.
Santiago FW , Halsey ES , Siles C , Vilcarromero S , Guevara C , Silvas JA , Ramal C , Ampuero JS , Aguilar PV , 2015. Long-term arthralgia after Mayaro virus infection correlates with sustained pro-inflammatory cytokine response. PLoS Negl Trop Dis 9: e0004104.
-
26.
Vasconcelo PFC , Calisher CH , 2016. Emergence of human arboviral diseases in the Americas, 2000–2016. Vector Borne Zoonotic Dis 16: 295–301.
-
27.
Gerberg EJ , Barnard DR , Ward RA , 1994. Manual for Mosquito Rearing and Experimental Techniques. Sacramento, CA: American Mosquito Control Association, Inc.
-
28.
Moreno BJ , Aldridge RL , Britch SC , Bayer BE , Kline J , Hahn DA , Chen C , Linthicum KJ , 2021. Preparing irradiated and marked male Aedes aegypti mosquitoes for release in an operational sterile insect technique program. J Vis Exp 169, doi: 10.3791/62260.
-
29.
Crawford JE , Clarke DW , Criswell V , Desnoyer M , Cornel D , Deegan B , 2020. Efficient production of male Wolbachia-infected Aedes aegypti mosquitoes enables large-scale suppression of wild populations. Nat Biotechnol 38: 482–492.
-
30.
Turell MJ , Wilson WC , Bennett KE , 2010. Potential for North American mosquitoes (Diptera: Culicidae) to transmit Rift Valley fever virus. J Med Entomol 47: 884–889.
-
31.
Turell MJ , Britch SC , Aldridge RL , Kline DL , Boohene C , Linthicum KJ , 2013. Potential for mosquitoes (Diptera: Culicidae) from Florida to transmit Rift Valley fever virus. J Med Entomol 50: 1111–1117.
-
32.
Moutailler S , Krida G , Schaffner F , Vazeille M , Failloux A-B , 2008. Potential vectors of Rift Valley fever virus in the Mediterranean region. Vector Borne Zoonotic Dis 8: 749–753.
-
33.
Lumley S , Hernández-Triana LM , Horton DL , Fernández de Marco MDM , Medlock JM , Hewson R , Fooks AR , Johnson N , 2018. Competence of mosquitoes native to the United Kingdom to support replication and transmission of Rift Valley fever virus. Parasit Vectors 11: 308.
-
34.
Brustolin M et al., 2017. Rift Valley fever virus and European mosquitoes: Vector competence of Culex pipiens and Stegomyia albopicta (= Aedes albopictus). Med Vet Entomol 31: 365–372.
-
35.
Moretti R , Lampazzi E , Damiani C , Fabbri G , Lombardi G , Pioli C , Desiderio A , Serrao A , Calvitti M , 2022. Increased biting rate and decreased Wolbachia density in irradiated Aedes mosquitoes. Parasit Vectors 15: 67.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 422 | 422 | 77 |
| Full Text Views | 20 | 20 | 9 |
| PDF Downloads | 23 | 23 | 13 |