ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Gallois E , Lamy T , Fines-Guyon M , Lobbedez T , Cattoir V , 2014. Recurrent peritoneal dialysis–related peritonitis caused by Microbacterium resistens. Diagn Microbiol Infect Dis 79: 111–113.
-
2.
Chorost MS , Smith NC , Hutter JN , Ong AC , Stam JA , McGann PT , Hinkle MK , Schaecher KE , Kamau E , 2018. Bacteraemia due to Microbacterium paraoxydans in a patient with chronic kidney disease, refractory hypertension and sarcoidosis. JMM Case Rep 5: e005169.
-
3.
Jacobs-Sera D et al., 2020. Genomic diversity of bacteriophages infecting Microbacterium spp. PLoS One 15: e0234636.
-
4.
Corretto E , Antonielli L , Sessitsch A , Höfer C , Puschenreiter M , Widhalm S , Swarnalakshmi K , Brader G , 2020. Comparative genomics of Microbacterium species to reveal diversity, potential for secondary metabolites and heavy metal resistance. Front Microbiol 11: 1869.
-
5.
Miyamoto M , Sakurada T , Oishi D , Koitabashi K , Hanada K , Takemura H , Shibagaki Y , Yasuda T , Kimura K , 2013. The first case report of peritoneal dialysis related peritonitis caused by Microbacterium paraoxydans. Clin Nephrol 79: 402–406.
-
6.
Gneiding K , Frodl R , Funke G , 2008. Identities of Microbacterium spp. encountered in human clinical specimens. J Clin Microbiol 46: 3646–3652.
-
7.
Amano J , Hase R , Otsuka Y , Tsuchimochi T , Noguchi Y , Igarashi S , 2019. Catheter-related bloodstream infection by Microbacterium paraoxydans in a pediatric patient with B-cell precursor acute lymphocytic leukemia: A case report and review of literature on Microbacterium bacteremia. J Infect Chemother 25: 806–810.
-
8.
Alonso-Echanove J , Shah SS , Valenti AJ , Dirrigl SN , Carson LA , Arduino MJ , Jarvis WR , 2001. Nosocomial outbreak of Microbacterium species bacteremia among cancer patients. J Infect Dis 184: 754–760.
-
9.
Adderson EE , Boudreaux JW , Hayden RT , 2008. Infections caused by coryneform bacteria in pediatric oncology patients. Pediatr Infect Dis J 27: 136–141.
-
10.
Laffineur K , Avesani V , Cornu G , Charlier J , Janssens M , Wauters G , Delmée M , 2003. Bacteremia due to a novel Microbacterium species in a patient with leukemia and description of Microbacterium paraoxydans sp. nov. J Clin Microbiol 41: 2242–2246.
-
11.
Choi HS , Bae EH , Ma SK , Kim SW , 2017. Peritoneal dialysis-related peritonitis caused by Microbacterium paraoxydans. Jpn J Infect Dis 70: 195–196.
-
12.
Enoch DA , Richardson MP , Hill RL , Scorer PM , Sismey A , 2011. Central venous catheter-related bacteraemia due to Microbacterium paraoxydans in a patient with no significant immunodeficiency. J Clin Pathol 64: 179–180.
-
13.
Mermel LA , Allon M , Bouza E , Craven DE , Flynn P , O’Grady NP , Raad II , Rijnders BJA , Sherertz RJ , Warren DK , 2009. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America. Clin Infect Dis 49: 1–45.
-
14.
Barberis C , Almuzara M , Join-Lambert O , Ramírez MS , Famiglietti A , Vay C , 2014. Comparison of the Bruker MALDI-TOF mass spectrometry system and conventional phenotypic methods for identification of Gram-positive rods. PLoS One 9: e106303.
-
15.
Lam PW , Naimark DM , Leis JA , 2018. Microbacterium peritonitis in peritoneal dialysis: A case report and review. Perit Dial Int 38: 9–13.
-
16.
Adames H , Baldoví S , Martin-Cleary C , Ortiz A , Esteban J , 2010. Peritonitis due to Microbacterium sp in a patient on cycler peritoneal dialysis. Perit Dial Int 30: 669–670.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 2542 | 2542 | 140 |
| Full Text Views | 78 | 78 | 4 |
| PDF Downloads | 100 | 100 | 4 |
Case Series: Microbacterium aurum Bacteremia in Immunosuppressed Patients—An Emerging Threat
Gerlin Varghese
Gerlin Varghese
Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
Search for other papers by Gerlin Varghese in
Current site
Google Scholar
PubMed
Search for other papers by Gerlin Varghese in
Current site
Google Scholar
PubMed
Deepika Sarawat
Deepika Sarawat
Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
Search for other papers by Deepika Sarawat in
Current site
Google Scholar
PubMed
Search for other papers by Deepika Sarawat in
Current site
Google Scholar
PubMed
Ashima Jamwal
Ashima Jamwal
Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
Search for other papers by Ashima Jamwal in
Current site
Google Scholar
PubMed
Search for other papers by Ashima Jamwal in
Current site
Google Scholar
PubMed
Sangram Singh Patel
Sangram Singh Patel
Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
Search for other papers by Sangram Singh Patel in
Current site
Google Scholar
PubMed
Search for other papers by Sangram Singh Patel in
Current site
Google Scholar
PubMed
Nidhi Tejan
Nidhi Tejan
Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
Search for other papers by Nidhi Tejan in
Current site
Google Scholar
PubMed
Search for other papers by Nidhi Tejan in
Current site
Google Scholar
PubMed
Chinmoy Sahu
Chinmoy Sahu
Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
Search for other papers by Chinmoy Sahu in
Current site
Google Scholar
PubMed
Search for other papers by Chinmoy Sahu in
Current site
Google Scholar
PubMed
ABSTRACT.
Blood stream infection with Microbacterium species in humans is rare and frequently linked to the presence of immunosuppressed conditions such as patients on chemotherapy or corticosteroids. Presence of indwelling catheters is also a potential risk factor for M. aurum infection. No case report has been documented in the literature regarding the pathogenic potential of M. aurum in causing bacteremia. This is the first case series reporting bacteremia by M. aurum describing the risk factors and sensitivity pattern of this pathogen. In this case series, we have described bacteremia caused by M. aurum. The risk factors and sensitivity pattern of this pathogen have also been evaluated. Here, we describe the clinical course and presentation of three patients whose blood culture showed growth of M. aurum. Indwelling venous catheter for hemodialysis or for chemotherapy for the treatment of acute lymphoblastic leukemia was found to be a risk factor in two patients. Rheumatoid arthritis was the underlying condition in the second patient and was started on immunosuppressants. Blood samples were collected during the febrile period. The blood culture samples of all these patients had pure isolates of M. aurum, identified by matrix-assisted laser desorption ionization–time of flight mass spectrometry. All three patients were managed according to the sensitivity reports and were discharged in stable condition.
Author Notes
Authors’ contributions: G. Varghese and D. Sarawat: conceptualization of work, data acquisition. A Jamwal and S. S. Patel: data analysis. N. Tejan: critical revision of the draft for important intellectual content. C. Sahu: final approval of the manuscript for publication.
Authors’ addresses: Gerlin Varghese, Deepika Sarawat, Ashima Jamwal, Sangram Singh Patel, Nidhi Tejan, and Chinmoy Sahu, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, E-mails: gerlinvarghese20@gmail.com, docdeepika14@gmail.com, ashi.jamwal@gmail.com, sangramresearch968@gmail.com, nidhiresearchsgpgi@gmail.com, and chinmoyresearch@gmail.com.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Gallois E , Lamy T , Fines-Guyon M , Lobbedez T , Cattoir V , 2014. Recurrent peritoneal dialysis–related peritonitis caused by Microbacterium resistens. Diagn Microbiol Infect Dis 79: 111–113.
-
2.
Chorost MS , Smith NC , Hutter JN , Ong AC , Stam JA , McGann PT , Hinkle MK , Schaecher KE , Kamau E , 2018. Bacteraemia due to Microbacterium paraoxydans in a patient with chronic kidney disease, refractory hypertension and sarcoidosis. JMM Case Rep 5: e005169.
-
3.
Jacobs-Sera D et al., 2020. Genomic diversity of bacteriophages infecting Microbacterium spp. PLoS One 15: e0234636.
-
4.
Corretto E , Antonielli L , Sessitsch A , Höfer C , Puschenreiter M , Widhalm S , Swarnalakshmi K , Brader G , 2020. Comparative genomics of Microbacterium species to reveal diversity, potential for secondary metabolites and heavy metal resistance. Front Microbiol 11: 1869.
-
5.
Miyamoto M , Sakurada T , Oishi D , Koitabashi K , Hanada K , Takemura H , Shibagaki Y , Yasuda T , Kimura K , 2013. The first case report of peritoneal dialysis related peritonitis caused by Microbacterium paraoxydans. Clin Nephrol 79: 402–406.
-
6.
Gneiding K , Frodl R , Funke G , 2008. Identities of Microbacterium spp. encountered in human clinical specimens. J Clin Microbiol 46: 3646–3652.
-
7.
Amano J , Hase R , Otsuka Y , Tsuchimochi T , Noguchi Y , Igarashi S , 2019. Catheter-related bloodstream infection by Microbacterium paraoxydans in a pediatric patient with B-cell precursor acute lymphocytic leukemia: A case report and review of literature on Microbacterium bacteremia. J Infect Chemother 25: 806–810.
-
8.
Alonso-Echanove J , Shah SS , Valenti AJ , Dirrigl SN , Carson LA , Arduino MJ , Jarvis WR , 2001. Nosocomial outbreak of Microbacterium species bacteremia among cancer patients. J Infect Dis 184: 754–760.
-
9.
Adderson EE , Boudreaux JW , Hayden RT , 2008. Infections caused by coryneform bacteria in pediatric oncology patients. Pediatr Infect Dis J 27: 136–141.
-
10.
Laffineur K , Avesani V , Cornu G , Charlier J , Janssens M , Wauters G , Delmée M , 2003. Bacteremia due to a novel Microbacterium species in a patient with leukemia and description of Microbacterium paraoxydans sp. nov. J Clin Microbiol 41: 2242–2246.
-
11.
Choi HS , Bae EH , Ma SK , Kim SW , 2017. Peritoneal dialysis-related peritonitis caused by Microbacterium paraoxydans. Jpn J Infect Dis 70: 195–196.
-
12.
Enoch DA , Richardson MP , Hill RL , Scorer PM , Sismey A , 2011. Central venous catheter-related bacteraemia due to Microbacterium paraoxydans in a patient with no significant immunodeficiency. J Clin Pathol 64: 179–180.
-
13.
Mermel LA , Allon M , Bouza E , Craven DE , Flynn P , O’Grady NP , Raad II , Rijnders BJA , Sherertz RJ , Warren DK , 2009. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America. Clin Infect Dis 49: 1–45.
-
14.
Barberis C , Almuzara M , Join-Lambert O , Ramírez MS , Famiglietti A , Vay C , 2014. Comparison of the Bruker MALDI-TOF mass spectrometry system and conventional phenotypic methods for identification of Gram-positive rods. PLoS One 9: e106303.
-
15.
Lam PW , Naimark DM , Leis JA , 2018. Microbacterium peritonitis in peritoneal dialysis: A case report and review. Perit Dial Int 38: 9–13.
-
16.
Adames H , Baldoví S , Martin-Cleary C , Ortiz A , Esteban J , 2010. Peritonitis due to Microbacterium sp in a patient on cycler peritoneal dialysis. Perit Dial Int 30: 669–670.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 2542 | 2542 | 140 |
| Full Text Views | 78 | 78 | 4 |
| PDF Downloads | 100 | 100 | 4 |