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1.
Sharma VK , Bhari N , Wadhwani AR , Bhatia R , 2018. Photo-patch and patch tests in patients with dermatitis over the photo-exposed areas: A study of 101 cases from a tertiary care centre in India. Australas J Dermatol 59: e1–e5.
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2.
Khurana A , Sardana K , Khurana A & Rani S Handbook of Eczema for Dermatologists. New Delhi, India: CBS Publishers, 15–23.
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3.
Fregert S, 1981. Patch testing. Fregert S, ed. Manual of Contact Dermatitis, 2nd ed. Copenhagen, Denmark: Munksgaard International Publishers, 71–81.
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4.
Lakshmi C , Srinivas CR , 2009. Parthenium the terminator: An update. Indian Dermatol Online J 3: 89–100.
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5.
Lepoittevin JP , Berl V , Giménez‐Arnau E , 2009. α‐Methylene‐γ‐butyrolactones: Versatile skin bioactive natural products. Chem Rec 9: 258–270.
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6.
Sharma VK , Verma P , Maharaja K , 2013. Parthenium dermatitis. Photochem Photobiol Sci 12: 85–94.
-
7.
Que SK , Brauer JA , Soter NA , Cohen DE , 2011. Chronic actinic dermatitis: An analysis at a single institution over 25 years. Dermatitis 22: 147–154.
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8.
Paek SY , Lim HW , 2014. Chronic actinic dermatitis. Dermatol Clin 32: 355–361.
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9.
Muddebihal A , Sardana K , Sinha S , Kumar D , 2023. Tofacitinib in refractory Parthenium-induced airborne allergic contact dermatitis. Contact Dermat 88: 150–152.
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10.
Vesely MD , Imaeda S , King BA , 2016. Tofacitinib citrate for the treatment of refractory, severe chronic actinic dermatitis. JAAD Case Rep 3: 4–6.
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11.
Dev A , Bishnoi A , Narang T , Vinay K , 2023. Recalcitrant chronic actinic dermatitis responding to tofacitinib: A case report. Indian J Dermatol Venereol Leprol 89: 600–602.
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12.
Dhir B , Meena SK , Sardana K , Sharath S , 2023. Use of tofacitinib in baricitinib-refractory atopic dermatitis: An example of JAK inhibitor switching. Pediatr Dermatol 41: 139–140.
-
13.
Duraisamy P , Jagadeesan S , Thomas J , 2022. Tofacitinib in the treatment of refractory eczemas: A case series. J Dermatolog Treat 33: 2873–2875.
| Past two years | Past Year | Past 30 Days | |
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| Abstract Views | 1910 | 1406 | 49 |
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Case Report: Mixed Airborne Contact Dermatitis–Chronic Actinic Dermatitis Pattern of Parthenium Dermatitis with Response to Tofacitinib Therapy
Ananta Khurana
Ananta Khurana
Department of Dermatology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India
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Sheetal Yadav
Sheetal Yadav
Department of Dermatology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India
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Kunal Chanana
Kunal Chanana
Department of Dermatology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India
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Kabir Sardana
Kabir Sardana
Department of Dermatology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India
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Aakash Vidholiya
Aakash Vidholiya
Department of Dermatology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India
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ABSTRACT.
Parthenium hysterophorus is the commonest cause of plant dermatitis in India. It classically causes airborne contact dermatitis (ABCD), characterized by pruritic, eczematous, and lichenified lesions involving predominantly the face and flexural areas. Over time, however, a transition to chronic actinic dermatitis (CAD) pattern, with prominent involvement of sun-exposed sites, may occur. Management involves strict protective measures and topical and oral corticosteroids or immunomodulatory agents but often leads to only limited success. We report a patient with a chronic and extensive mixed ABCD-CAD pattern of parthenium dermatitis recalcitrant to conventional treatment, with rapid resolution after initiation of treatment with tofacitinib.
Author Notes
Authors’ addresses: Ananta Khurana, Sheetal Yadav, Kunal Chanana, Kabir Sardana, and Aakash Vidholiya, Department of Dermatology, Atal Bihari Vajpayee Institute of Medical Sciences, and Dr. Ram Manohar Lohia Hospital, New Delhi, India, E-mails: drananta2014@gmail.com, sheetalyadav521@gmail.com, drkunalchanana@gmail.com, article.sardana@gmail.com, and aakashvidholiya@gmail.com.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Sharma VK , Bhari N , Wadhwani AR , Bhatia R , 2018. Photo-patch and patch tests in patients with dermatitis over the photo-exposed areas: A study of 101 cases from a tertiary care centre in India. Australas J Dermatol 59: e1–e5.
-
2.
Khurana A , Sardana K , Khurana A & Rani S Handbook of Eczema for Dermatologists. New Delhi, India: CBS Publishers, 15–23.
-
3.
Fregert S, 1981. Patch testing. Fregert S, ed. Manual of Contact Dermatitis, 2nd ed. Copenhagen, Denmark: Munksgaard International Publishers, 71–81.
-
4.
Lakshmi C , Srinivas CR , 2009. Parthenium the terminator: An update. Indian Dermatol Online J 3: 89–100.
-
5.
Lepoittevin JP , Berl V , Giménez‐Arnau E , 2009. α‐Methylene‐γ‐butyrolactones: Versatile skin bioactive natural products. Chem Rec 9: 258–270.
-
6.
Sharma VK , Verma P , Maharaja K , 2013. Parthenium dermatitis. Photochem Photobiol Sci 12: 85–94.
-
7.
Que SK , Brauer JA , Soter NA , Cohen DE , 2011. Chronic actinic dermatitis: An analysis at a single institution over 25 years. Dermatitis 22: 147–154.
-
8.
Paek SY , Lim HW , 2014. Chronic actinic dermatitis. Dermatol Clin 32: 355–361.
-
9.
Muddebihal A , Sardana K , Sinha S , Kumar D , 2023. Tofacitinib in refractory Parthenium-induced airborne allergic contact dermatitis. Contact Dermat 88: 150–152.
-
10.
Vesely MD , Imaeda S , King BA , 2016. Tofacitinib citrate for the treatment of refractory, severe chronic actinic dermatitis. JAAD Case Rep 3: 4–6.
-
11.
Dev A , Bishnoi A , Narang T , Vinay K , 2023. Recalcitrant chronic actinic dermatitis responding to tofacitinib: A case report. Indian J Dermatol Venereol Leprol 89: 600–602.
-
12.
Dhir B , Meena SK , Sardana K , Sharath S , 2023. Use of tofacitinib in baricitinib-refractory atopic dermatitis: An example of JAK inhibitor switching. Pediatr Dermatol 41: 139–140.
-
13.
Duraisamy P , Jagadeesan S , Thomas J , 2022. Tofacitinib in the treatment of refractory eczemas: A case series. J Dermatolog Treat 33: 2873–2875.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1910 | 1406 | 49 |
| Full Text Views | 49 | 43 | 4 |
| PDF Downloads | 59 | 53 | 4 |