Case Report: Allergic Bronchopulmonary Aspergillosis and Tropical Pulmonary Eosinophilia Co-Occurrence Masquerading as Refractory Allergic Bronchopulmonary Aspergillosis

Manish Singh Department of Pulmonary Medicine, Command Hospital (NC), Udhampur, India;

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Deepu K. Peter Department of Pulmonary Medicine, Command Hospital (NC), Udhampur, India;

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Simple Gupta Department of Ophthalmology, Command Hospital (NC), Udhampur, India;

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Vandana Rani V Department of Pediatrics, Command Hospital (NC), Udhampur, India;

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Shalendra Singh Deparment of Anaesthesia and Critical Care, Command Hospital (NC), Udhampur, India

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ABSTRACT.

Pulmonary infiltrates with eosinophilia are a heterogeneous group of disorders that are characterized by pulmonary infiltrates on chest radiograph and elevated levels of eosinophils in the peripheral blood. Among patients with these disorders, reports of either allergic bronchopulmonary aspergillosis (ABPA) or tropical pulmonary eosinophilia (TPE) are common. However, the simultaneous occurrence of ABPA and TPE is not often reported. We present the case of a young man with a history of asthma who was diagnosed with ABPA and TPE. Initially, the patient exhibited a partial response to treatment of ABPA, but persistent symptoms and eosinophilia led to suspicion and subsequent diagnosis of TPE. With implementation of antifilarials and steroids, the patient experienced satisfactory clinical and serological improvements. This case underscores the importance of considering multiple diagnoses in patients with overlapping symptoms and highlights the need for comprehensive management strategies in complex lung diseases.

Author Notes

Disclosures: Written consent was obtained from the patients regarding the inclusion of material about themselves. They acknowledged that they cannot be identified from the article and that their data have been fully anonymized.

Authors’ addresses: Manish Singh and Deepu K. Peter, Department of Pulmonary Medicine, Command Hospital (NC), Udhampur, India, E-mails: manish.6026@gmail.com and drdeepupeter@gmail.com. Simple Gupta, Department of Ophthalmology, Command Hospital (NC), Udhampur, India, E-mail: drsimplegupta7402@gmail.com. Vandana Rani V., Department of Pediatrics, Command Hospital (NC), Udhampur, India, E-mail: vandyseutopia@gmail.com. Shalendra Singh, Department of Anaesthesia and Critical Care, Command Hospital (NC), Udhampur, India, E-mail: drsinghafmc@gmail.com.

Address correspondence to Deepu K. Peter, Department of Pulmonary Medicine, Command Hospital (NC), Udhampur 182101, India. E-mail: drdeepupeter@gmail.com
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