| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 364 | 125 | 5 |
| Full Text Views | 5 | 1 | 0 |
| PDF Downloads | 4 | 2 | 0 |
Intramuscular Amopyroquin for Acute Malaria
Mark T. Hoekenga
Mark T. Hoekenga
Cincinnati, Ohio
Search for other papers by Mark T. Hoekenga in
Current site
Google Scholar
PubMed
Search for other papers by Mark T. Hoekenga in
Current site
Google Scholar
PubMed
Summary and Conclusions
Amopyroquin (Propoquin®), a relatively new antimalarial agent with the chemical formula 4 - (7 - chloro - 4 - quinolylamino) - a - 1 - pyrolidyl-o-cresol dihydrochloride, was given by intramuscular injection to 525 Panamanians with acute malaria. Patients generally responded very well to this therapy, and there was no evidence of toxicity. A comparison has been made with a series of malaria patients treated with parenteral chloroquine or parenteral hydroxy-chloroquine.
Intramuscular amopyroquin is recommended for treatment of malaria in those patients who require a parenteral medication. In the majority of adult patients, a single injection of 90 to 150 mg base achieved the desired results, with proportionately smaller quantities sufficing for younger children. Multiple injections may be given at the discretion of the physician.
Author Notes
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 364 | 125 | 5 |
| Full Text Views | 5 | 1 | 0 |
| PDF Downloads | 4 | 2 | 0 |