Case Report: Leptospirosis Complicated by Persistent, Bilateral Sensorineural Hearing Loss

Stuart Campbell Division of Medicine, Cairns Hospital, Cairns, Australia;

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James Stewart Division of Medicine, Cairns Hospital, Cairns, Australia;

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Gavin Quail Department of Surgery, Cairns Hospital, Cairns, Australia;

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Grant Withey Department of Radiology, Cairns Hospital, Cairns, Australia;

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Simon Smith Division of Medicine, Cairns Hospital, Cairns, Australia;

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Josh Hanson Division of Medicine, Cairns Hospital, Cairns, Australia;
The Kirby Institute, University of New South Wales, Sydney, Australia

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ABSTRACT.

The clinical manifestations of leptospirosis range from mild to life-threatening and can impact on multiple organ systems. A wide array of neurological manifestations of leptospirosis have been reported, although the pathophysiology of neuroleptospirosis remains incompletely understood. We present a case of leptospirosis complicated by bilateral sensorineural deafness, with nodular meningitis demonstrated in the internal auditory meatus on magnetic resonance imaging. The patient was treated with doxycycline, ceftriaxone, systemic and topical steroids, and hyperbaric oxygen therapy, with modest, but incomplete, improvement.

Author Notes

Authors’ addresses: Stuart Campbell, James Stewart, and Simon Smith, Department of Medicine, Cairns Hospital, Cairns, Australia, E-mails: stuartc345@gmail.com, james.stewart7@health.qld.gov.au, and simon.smith2@health.qld.gov.au. Gavin Quail, Department of Surgery, Cairns Hospital, Cairns, Australia, E-mail: gavin.quail@health.qld.gov.au. Grant Withey, Department of Radiology, Cairns Hospital, Cairns, Australia, E-mail: grant.withey@health.qld.gov.au. Josh Hanson, Department of Medicine, Cairns Hospital, Cairns, Australia, and The Kirby Institute, University of New South Wales, Sydney, Australia, E-mail: jhanson@kirby.unsw.edu.au.

Address correspondence to Josh Hanson, The Kirby Institute, University of New South Wales, Wallace Wurth Bldg., Sydney, NSW 2052, Australia. E-mail: jhanson@kirby.unsw.edu.au
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