Case Report: Extensive Facial Cutaneous Leishmaniasis in a Neonate

Sapir Itzhaki Gabay Department of Dermatology, Soroka University Medical Center, Beer-Sheva, Israel;
Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel;

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Yuliya Valdman-Grinshpoun Department of Dermatology, Soroka University Medical Center, Beer-Sheva, Israel;
Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel;

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Galina Ling Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel;

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Shalom Ben-Shimol Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel;
Pediatric Infectious Disease Unit, Soroka University Medical Center, Beer Sheva, Israel;

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Gidon Test Pediatric Emergency Department, Soroka University Medical Center, Beer-Sheva, Israel;

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Or Kaplan Pediatric Emergency Department, Soroka University Medical Center, Beer-Sheva, Israel;

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Amir Horev Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel;
Pediatric Dermatology Service, Soroka University Medical Center, Beer-Sheva, Israel

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ABSTRACT.

Cutaneous leishmaniasis (CL) is a skin infection caused by various species of the Leishmania parasite and is spread by the bite of an infected female sandfly. In southern Israel, CL caused by Leishmania major is endemic. Cutaneous leishmaniasis is considered a self-limiting disease, characterized by progressive, long-lasting nodulo-ulcerative skin lesions, which usually resolve in several months to years, and leads to scarring, cosmetic disfigurement, and future stigmatization. Although CL is a common disease among children, reports of CL in children younger than 1 year are rare. We present a case of extensive facial CL in an infant whose initial lesions appeared only 25 days after birth. The patient was treated with intravenous liposomal amphotericin B. Two months later, marked improvement was seen, with complete resolution of the inflammation and atrophic scar formation. To our knowledge, this is the earliest age of CL published to date.

Author Notes

Address correspondence to Amir Horev, Soroka University Medical Center, Hanesiim St., Beer-Sheva 84101, Israel. E-mail: amirhr@clalit.org.il

Authors’ addresses: Sapir Itzhaki Gabay and Yuliya Valdman-Grinshpoun, Department of Dermatology, Soroka University Medical Center, Beer-Sheva, Israel, and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel, E-mails: sapirisarah@gmail.com and yuliava@clalit.org.il. Galina Ling, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel, E-mail: galinali@clalit.org.il. Shalom Ben-Shimol, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel, and Pediatric Infectious Disease Unit, Soroka University Medical Center, Beer Sheva, Israel, E-mail: bench@bgu.ac.il. Gidon Test and Or Kaplan, Pediatric Emergency Department, Soroka University Medical Center, Beer-Sheva, Israel, E-mails: gidontest@clalit.org.il and kaplan.or7@gmail.com. Amir Horev, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel, and Pediatric Dermatology Service, Soroka University Medical Center, Beer-Sheva, Israel, E-mail: amirhr@clalit.org.il.

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