Zemore ZM, Wills BK, 2023. Kissing Bug Bite. Treasure Island, FL: StatPearls Publishing.
Rassi A Jr , Rassi A, Marcondes de Rezende J, 2012. American trypanosomiasis (Chagas disease). Infect Dis Clin North Am 26: 275–291.
Bern C, 2015. Chagas’ disease. N Engl J Med 373: 456–466.
Rassi A Jr , Rassi A, Marin-Neto JA, 2010. Chagas disease. Lancet 375: 1388–1402.
Nunes MCP et al., 2018. Chagas cardiomyopathy: an update of current clinical knowledge and management: a scientific statement from the American Heart Association. Circulation 138: e169–e209.
Rassi A, de Rezende JM, Luquetti AO, Rassi A Jr , Elleria J & Tibayrenc M American Trypanosomiasis (Chagas disease): One Hundred Years of Research, 1st edition. Burlington, MA: Elsevier, 709–741.
Martins MCL, Miyazaki DL, Gabiatti CCT, Silva LP, Macedo LT, Siqueira NS, Andreollo NA, Carvalheira JBC, 2019. Chagasic megaesophagus-associated carcinoma: clinical pattern and outcomes. J Glob Oncol 5: 1–5.
Pino-Marín A, Medina-Rincón GJ, Gallo-Bernal S, Duran-Crane A, Arango Duque ÁI, Rodríguez MJ, Medina-Mur R, Manrique FT, Forero JF, Medina HM, 2021. Chagas cardiomyopathy: from Romaña sign to heart failure and sudden cardiac death. Pathogens 10: 505.
Migration Policy Institute , n.d. State Immigration Data Profiles: United States. Available at: https://www.migrationpolicy.org/data/state-profiles/state/demographics/US. Accessed June 24, 2023.
Irish A, Whitman JD, Clark EH, Marcus R, Bern C, 2022. Updated estimates and mapping for prevalence of Chagas disease among adults, United States. Emerg Infect Dis 28: 1313–1320.
United States Census Bureau , n.d. QuickFacts, Suffolk County, New York. Available at: https://www.census.gov/quickfacts/fact/table/suffolkcountynewyork/HCN010217. Accessed June 24, 2023.
Shah V et al., 2014. Field evaluation of the InBios Chagas detect plus rapid test in serum and whole-blood specimens in Bolivia. Clin Vaccine Immunol 21: 1645–1649.
Whitman JD, Bulman CA, Gunderson EL, Irish AM, Townsend RL, Stramer SL, Sakanari JA, Bern C, 2019. Chagas disease serological test performance in U.S. blood donor specimens. J Clin Microbiol 57: e01271–e01219.
Migration Policy Institute , n.d. State Immigration Data Profiles: New York: Demographics & Social. Available at: https://www.migrationpolicy.org/data/state-profiles/state/demographics/NY. Accessed June 24, 2023.
Meymandi SK, Forsyth CJ, Soverow J, Hernandez S, Sanchez D, Montgomery SP, Traina M, 2017. Prevalence of Chagas disease in the Latin American-born population of Los Angeles. Clin Infect Dis 64: 1182–1188.
Traina MI, Hernandez S, Sanchez DR, Dufani J, Salih M, Abuhamidah AM, Olmedo W, Bradfield JS, Forsyth CJ, Meymandi SK, 2017. Prevalence of Chagas disease in a U.S. population of Latin American immigrants with conduction abnormalities on electrocardiogram. PLoS Negl Trop Dis 11: e0005244.
Traina MI, Sanchez DR, Hernandez S, Bradfield JS, Labedi MR, Ngab TA, Steurer F, Montgomery SP, Meymandi SK, 2015. Prevalence and impact of Chagas disease among Latin American immigrants with nonischemic cardiomyopathy in Los Angeles, California. Circ Heart Fail 8: 938–943.
Zheng C et al., 2020. Chagas disease in the New York City metropolitan area. Open Forum Infect Dis 7: ofaa156.
Lidani KCF, Andrade FA, Bavia L, Damasceno FS, Beltrame MH, Messias-Reason IJ, Sandri TL, 2019. Chagas disease: from discovery to a worldwide health problem. Front Public Health 7: 166.
Past two years | Past Year | Past 30 Days | |
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Abstract Views | 1576 | 906 | 94 |
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This cross-sectional study estimated a one-time point seroprevalence rate of Chagas disease among people of Latin American descent in Suffolk County, Long Island, New York. Subjects who met the inclusion criteria were screened using the Chagas Detect Plus Rapid Test (InBios, Seattle, WA) with confirmation via Trypanosoma cruzi enzyme immunoassay and T. cruzi immunoblot assay. Administration of a questionnaire regarding demographics and risk factors followed. A seroprevalence rate of 10.74% was found. Identified risk factors included prior residence in a palm leaf house (odds ratio [OR], 10.42; P = 0.003; 95% CI, 2.18–49.76), residence in a house with triatomines (OR, 9.03; P = 0.006; 95% CI, 1.90–42.88), and history of triatomine bite (OR, 9.52; P = 0.009; 95% CI, 1.75–51.77). Our findings emphasize the importance of this frequently underdiagnosed disease and help highlight the importance of early screening among high-risk populations.
Financial support: This study was funded, in part, by the
Authors’ addresses: Miguel A. Saldivar, Yamil E. Michelen, Lucia Milla, and Eric Sin, Division of Infectious Diseases, Department of Internal Medicine, Stony Brook University, Stony Brook, NY, E-mails: miguel.saldivar@stonybrookmedicine.edu, yamilmichelen@gmail.com, lucia.milla@tuftsmedicine.org, and eric.sin@stonybrookmedicine.edu. Andreas P. Kalogeropoulos, Division of Cardiology, Department of Internal Medicine, Stony Brook University, Stony Brook, NY, E-mail: andreas.kalogeropoulos@stonybrookmedicine.edu. Harriet L. Hellman, Department of Pediatrics, Hampton Community Health Care, Southampton, NY, E-mail: hchc@optonline.net. Robert H. Gilman, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, E-mail: gilmanbob@gmail.com. Luis A. Marcos, Division of Infectious Diseases, Department of Internal Medicine, Stony Brook University, Stony Brook, NY, and Department of Microbiology and Immunology, Stony Brook University, Stony Brook, NY, E-mail: luis.marcosraymundo@stonybrookmedicine.edu.
Zemore ZM, Wills BK, 2023. Kissing Bug Bite. Treasure Island, FL: StatPearls Publishing.
Rassi A Jr , Rassi A, Marcondes de Rezende J, 2012. American trypanosomiasis (Chagas disease). Infect Dis Clin North Am 26: 275–291.
Bern C, 2015. Chagas’ disease. N Engl J Med 373: 456–466.
Rassi A Jr , Rassi A, Marin-Neto JA, 2010. Chagas disease. Lancet 375: 1388–1402.
Nunes MCP et al., 2018. Chagas cardiomyopathy: an update of current clinical knowledge and management: a scientific statement from the American Heart Association. Circulation 138: e169–e209.
Rassi A, de Rezende JM, Luquetti AO, Rassi A Jr , Elleria J & Tibayrenc M American Trypanosomiasis (Chagas disease): One Hundred Years of Research, 1st edition. Burlington, MA: Elsevier, 709–741.
Martins MCL, Miyazaki DL, Gabiatti CCT, Silva LP, Macedo LT, Siqueira NS, Andreollo NA, Carvalheira JBC, 2019. Chagasic megaesophagus-associated carcinoma: clinical pattern and outcomes. J Glob Oncol 5: 1–5.
Pino-Marín A, Medina-Rincón GJ, Gallo-Bernal S, Duran-Crane A, Arango Duque ÁI, Rodríguez MJ, Medina-Mur R, Manrique FT, Forero JF, Medina HM, 2021. Chagas cardiomyopathy: from Romaña sign to heart failure and sudden cardiac death. Pathogens 10: 505.
Migration Policy Institute , n.d. State Immigration Data Profiles: United States. Available at: https://www.migrationpolicy.org/data/state-profiles/state/demographics/US. Accessed June 24, 2023.
Irish A, Whitman JD, Clark EH, Marcus R, Bern C, 2022. Updated estimates and mapping for prevalence of Chagas disease among adults, United States. Emerg Infect Dis 28: 1313–1320.
United States Census Bureau , n.d. QuickFacts, Suffolk County, New York. Available at: https://www.census.gov/quickfacts/fact/table/suffolkcountynewyork/HCN010217. Accessed June 24, 2023.
Shah V et al., 2014. Field evaluation of the InBios Chagas detect plus rapid test in serum and whole-blood specimens in Bolivia. Clin Vaccine Immunol 21: 1645–1649.
Whitman JD, Bulman CA, Gunderson EL, Irish AM, Townsend RL, Stramer SL, Sakanari JA, Bern C, 2019. Chagas disease serological test performance in U.S. blood donor specimens. J Clin Microbiol 57: e01271–e01219.
Migration Policy Institute , n.d. State Immigration Data Profiles: New York: Demographics & Social. Available at: https://www.migrationpolicy.org/data/state-profiles/state/demographics/NY. Accessed June 24, 2023.
Meymandi SK, Forsyth CJ, Soverow J, Hernandez S, Sanchez D, Montgomery SP, Traina M, 2017. Prevalence of Chagas disease in the Latin American-born population of Los Angeles. Clin Infect Dis 64: 1182–1188.
Traina MI, Hernandez S, Sanchez DR, Dufani J, Salih M, Abuhamidah AM, Olmedo W, Bradfield JS, Forsyth CJ, Meymandi SK, 2017. Prevalence of Chagas disease in a U.S. population of Latin American immigrants with conduction abnormalities on electrocardiogram. PLoS Negl Trop Dis 11: e0005244.
Traina MI, Sanchez DR, Hernandez S, Bradfield JS, Labedi MR, Ngab TA, Steurer F, Montgomery SP, Meymandi SK, 2015. Prevalence and impact of Chagas disease among Latin American immigrants with nonischemic cardiomyopathy in Los Angeles, California. Circ Heart Fail 8: 938–943.
Zheng C et al., 2020. Chagas disease in the New York City metropolitan area. Open Forum Infect Dis 7: ofaa156.
Lidani KCF, Andrade FA, Bavia L, Damasceno FS, Beltrame MH, Messias-Reason IJ, Sandri TL, 2019. Chagas disease: from discovery to a worldwide health problem. Front Public Health 7: 166.
Past two years | Past Year | Past 30 Days | |
---|---|---|---|
Abstract Views | 1576 | 906 | 94 |
Full Text Views | 319 | 257 | 4 |
PDF Downloads | 76 | 30 | 5 |