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Chikungunya virus, a mosquito-borne alphavirus, causes acute febrile illness with polyarthralgia. Groups at risk for severe disease include neonates, people with underlying medical conditions, and those aged ≥ 65 years. Several chikungunya vaccines are in late clinical development with licensure expected in the United States during 2023. We administered a questionnaire to randomly selected households in the U.S. Virgin Islands (USVI) to assess interest in a hypothetical chikungunya vaccine. Estimates were calibrated to age and sex of USVI population, and univariate and multivariable analyses were performed. Of 966 participants, 520 (adjusted 56%, 95% CI = 51–60%) were interested in receiving the vaccine. Of 446 participants not interested in vaccination, 203 (adjusted 47%, 95% CI = 41–52%) cited safety concerns as the reason. Educational efforts addressing vaccine safety concerns and risk factors for severe disease would likely improve vaccine acceptability and uptake among those most at risk.
Disclosures: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the CDC.
Authors’ addresses: Emily J. Curren and Morgan J. Hennessey, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, and Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, E-mails: firstname.lastname@example.org and email@example.com. Esther M. Ellis, United States Virgin Islands Department of Health, Christiansted, U.S. Virgin Islands, E-mail: firstname.lastname@example.org. Mark J. Delorey, Marc Fischer, and J. Erin Staples, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, E-mails: email@example.com, firstname.lastname@example.org, and email@example.com.