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Leprosy, a chronic infectious disease, and psoriasis, an inflammatory disorder, are distinct entities. Epidemiology data show that these two diseases are almost mutually exclusive, with only a few reported cases of their coexistence. Here, we present the case of a patient manifesting intermingled psoriatic and leprosy lesions diagnosed as borderline lepromatous leprosy and plaque psoriasis. Of note, Mycobacterium leprae bacilli were detected not only in the two types of lesions but also in normal-appearing skin and blood.
Authors’ addresses: Jinghui Li, Hong Liu, and Furen Zhang, Shandong Provincial Hospital for Skin Diseases, Cheeloo College of Medicine, Shandong University, Jinan, China, and Shandong Provincial Hospital of Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China, E-mails: email@example.com, firstname.lastname@example.org, and email@example.com. Xi’an Fu, Lele Sun, and Xiaotong Xue, Shandong Provincial Hospital of Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China, E-mails: firstname.lastname@example.org, email@example.com, and firstname.lastname@example.org.