Case Report: Lepromatous Leprosy and Psoriasis: An Uncommon Coincidence

Jinghui Li Shandong Provincial Hospital for Skin Diseases, Cheeloo College of Medicine, Shandong University, Jinan, China;
Shandong Provincial Hospital of Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China

Search for other papers by Jinghui Li in
Current site
Google Scholar
PubMed
Close
,
Xi’an Fu Shandong Provincial Hospital of Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China

Search for other papers by Xi’an Fu in
Current site
Google Scholar
PubMed
Close
,
Lele Sun Shandong Provincial Hospital of Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China

Search for other papers by Lele Sun in
Current site
Google Scholar
PubMed
Close
,
Xiaotong Xue Shandong Provincial Hospital of Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China

Search for other papers by Xiaotong Xue in
Current site
Google Scholar
PubMed
Close
,
Hong Liu Shandong Provincial Hospital for Skin Diseases, Cheeloo College of Medicine, Shandong University, Jinan, China;
Shandong Provincial Hospital of Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China

Search for other papers by Hong Liu in
Current site
Google Scholar
PubMed
Close
, and
Furen Zhang Shandong Provincial Hospital for Skin Diseases, Cheeloo College of Medicine, Shandong University, Jinan, China;
Shandong Provincial Hospital of Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China

Search for other papers by Furen Zhang in
Current site
Google Scholar
PubMed
Close
Restricted access

ABSTRACT.

Leprosy, a chronic infectious disease, and psoriasis, an inflammatory disorder, are distinct entities. Epidemiology data show that these two diseases are almost mutually exclusive, with only a few reported cases of their coexistence. Here, we present the case of a patient manifesting intermingled psoriatic and leprosy lesions diagnosed as borderline lepromatous leprosy and plaque psoriasis. Of note, Mycobacterium leprae bacilli were detected not only in the two types of lesions but also in normal-appearing skin and blood.

Author Notes

Address correspondence to Hong Liu, Shandong Provincial Hospital of Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, 27397 Jingshi Rd., Jinan 250022, China. E-mail: hongyue2519@hotmail.com

Authors’ addresses: Jinghui Li, Hong Liu, and Furen Zhang, Shandong Provincial Hospital for Skin Diseases, Cheeloo College of Medicine, Shandong University, Jinan, China, and Shandong Provincial Hospital of Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China, E-mails: hh3903@sina.com, hongyue2519@hotmail.com, and zhangfuren@hotmail.com. Xi’an Fu, Lele Sun, and Xiaotong Xue, Shandong Provincial Hospital of Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China, E-mails: f19830827@126.com, 438065194@qq.com, and m17865138356@163.com.

  • 1.

    Cheng X et al., 2019. Development and evaluation of a droplet digital PCR assay for the diagnosis of paucibacillary leprosy in skin biopsy specimens. PLoS Negl Trop Dis 13: e0007284.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 2.

    Kumar B, Raychaudhuri SP, Vossough S, Farber EM, 1992. The rare co-existence of leprosy and psoriasis. Int J Dermatol 31: 551554.

  • 3.

    Christophers E, 2001. Psoriasis-epidemiology and clinical spectrum. Clin Exp Dermatol 26: 314320.

  • 4.

    Sheikh UA, Hill C, 2020. Case report: leprosy and psoriasis: a rare coexistence. Am J Trop Med Hyg 103: 206208.

  • 5.

    Dogra S, Kaur I, Kumar B, 2003. Leprosy and psoriasis: an enigmatic relationship. Int J Lepr Other Mycobact Dis 71: 341344.

  • 6.

    Bassukas ID, Gaitanis G, Hundeiker M, 2012. Leprosy and the natural selection for psoriasis. Med Hypotheses 78: 183190.

  • 7.

    Steinbach S, Vordermeier HM, Jones GJ, 2016. CD4+ and γδ T cells are the main producers of IL-22 and IL-17A in lymphocytes from mycobacterium bovis-infected cattle. Sci Rep 6:29990.

    • PubMed
    • Search Google Scholar
    • Export Citation
Past two years Past Year Past 30 Days
Abstract Views 4868 2777 107
Full Text Views 374 30 0
PDF Downloads 203 33 1
 

 

 

 
 
Affiliate Membership Banner
 
 
Research for Health Information Banner
 
 
CLOCKSS
 
 
 
Society Publishers Coalition Banner
Save