Case Report: Tuberculosis-Induced Autoimmune Hemolytic Anemia

Seham M. Alebbi Department of Medical Education, Hamad Medical Corporation, Doha, Qatar;

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Aalaa Kambal Clinical Imaging Department, Hamad Medical Corporation, Doha, Qatar;

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Hayan Abo Samra Department of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar;
Histopathology Department, Hamad Medical Corporation, Doha, Qatar;

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Mouhammad Z. Sharaf Eldean Department of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar;
Histopathology Department, Hamad Medical Corporation, Doha, Qatar;

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Shehab Fareed Mohamed Department of Hematology and Medical Oncology, National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar;

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Shaikha D. Al-Shokri Department of Medical Education, Hamad Medical Corporation, Doha, Qatar;
Department of Internal Medicine, Case Western Reserve University–MetroHealth Medical Center, Cleveland, Ohio

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ABSTRACT.

Tuberculosis (TB) is an infectious disease that affects different organs, causing multiple complications, including hematological sequelae. One of the most common TB-hematological complications is anemia of chronic disease. Very rarely autoimmune hemolytic anemia (AIHA) has been reported as an uncommon manifestation of TB. In this case, we present a female who presented with refractory AIHA, which was attributed to disseminated TB. The patient responded well to steroids, anti-TB medications, and rituximab.

Author Notes

Correspondence to Shaikha D. Al-Shokri, Department of Internal Medicine, Case Western Reserve University–MetroHealth Medical Center, 2500 Metrohealth Dr., Cleveland, OH 44109. E-mail: salshokri@hamad.qa

These authors contributed equally to this work.

Disclosure: This article was approved by Hamad Medical Corporation Medical Research Center. This research was conducted ethically in accordance with the World Medical Association Declaration of Helsinki.

Authors’ addresses: Seham M. Alebbi, Department of Medical Education, Hamad Medical Corporation, Doha, Qatar, E-mail: salebbi@hamad.qa. Aalaa Kambal, Clinical Imaging Department, Hamad Medical Corporation, Doha, Qatar, E-mail: akambal@hamad.qa. Hayan Abo Samra and Mouhammad Z. Sharaf Eldean, Department of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar, E-mails: hsamra@hamad.qa and meldean@hamad.qa. Shehab Fareed Mohamed, Department of Hematology and Medical Oncology, National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar, E-mail smohamed22@hamad.qa. Shaikha D. Al-Shokri, Department of Medical Education, Hamad Medical Corporation, Doha, Qatar and Department of Internal Medicine, Case Western Reserve University–MetroHealth Medical Center, Cleveland, Ohio, E-mail: salshokri@hamad.qa.

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