• 1.

    Gassiep I, Armstrong M, Norton R, 2020. Human melioidosis. Clin Microbiol Rev 33: e00006e00019.

  • 2.

    Chakravorty A, Heath C, 2019. Melioidosis: an updated review. Aust J Gen Pract 48: 327332.

  • 3.

    Karunanayake P, 2022. Melioidosis: clinical aspects. Clin Med (Lond) 22: 68.

  • 4.

    Yaisawang S, Asawaphureekorn S, Chetchotisakd P, Wongratanacheewin S, Pakdee P, 2018. Ocular involvement in melioidosis: a 23-year retrospective review. J Ophthalmic Inflamm Infect 8: 5.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 5.

    Siripanthong S, Teerapantuwat S, Prugsanusak W, Suputtamongkol Y, Viriyasithavat P, Chaowagul W, Dance DA, White NJ, 1991. Corneal ulcer caused by Pseudomonas pseudomallei: report of three cases. Rev Infect Dis 13: 335337.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 6.

    Lau SKP, Sridhar S, Ho CC, Chow WN, Lee KC, Lam CW, Yuen KY, Woo PC, 2015. Laboratory diagnosis of melioidosis: past, present and future. Exp Biol Med (Maywood) 240: 742751.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 7.

    Birnie E, Biemond JJ, Wiersinga WJ, 2022. Drivers of melioidosis endemicity: epidemiological transition, zoonosis, and climate change. Curr Opin Infect Dis 35: 196204.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 8.

    Ting DSJ, Ho CS, Deshmukh R, Said DG, Dua HS, 2021. Infectious keratitis: an update on epidemiology, causative microorganisms, risk factors, and antimicrobial resistance. Eye (Lond) 35: 10841101.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 9.

    Limmathurotsakul D, Wongratanacheewin S, Teerawattanasook N, Wongsuvan G, Chaisuksant S, Chetchotisakd P, Chaowagul W, Day NP, Peacock SJ, 2010. Increasing incidence of human melioidosis in Northeast Thailand. Am J Trop Med Hyg 82: 11131117.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 10.

    Cabrera-Aguas M, Khoo P, Watson SL, 2022. Infectious keratitis: a review. Clin Exp Ophthalmol 50: 543562.

  • 11.

    Karkhur S, Soni D, Sharma B, 2022. A novel technique of full-thickness scleral debridement in fulminant necrotising infectious scleritis and its outcomes: a consecutive case series. Int Ophthalmol 42: 581592.

    • PubMed
    • Search Google Scholar
    • Export Citation
  • 12.

    Pradhan ZS, Jacob P, 2013. Infectious scleritis: clinical spectrum and management outcomes in India. Indian J Ophthalmol 61: 590593.

Past two years Past Year Past 30 Days
Abstract Views 1708 1708 64
Full Text Views 41 41 16
PDF Downloads 55 55 19
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Case Report: Burkholderia pseudomallei–Caused Sclerokeratitis

Onsiri ThanathaneeDepartment of Ophthalmology, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand

Search for other papers by Onsiri Thanathanee in
Current site
Google Scholar
PubMed
Close
,
Korawin CharoensukDepartment of Ophthalmology, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand

Search for other papers by Korawin Charoensuk in
Current site
Google Scholar
PubMed
Close
,
Yuwarat UthairatDepartment of Ophthalmology, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand

Search for other papers by Yuwarat Uthairat in
Current site
Google Scholar
PubMed
Close
,
Suparat LaohapitakvornDepartment of Ophthalmology, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand

Search for other papers by Suparat Laohapitakvorn in
Current site
Google Scholar
PubMed
Close
,
Orapin AnutarapongpanDepartment of Ophthalmology, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand

Search for other papers by Orapin Anutarapongpan in
Current site
Google Scholar
PubMed
Close
, and
Olan Suwan-apichonDepartment of Ophthalmology, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand

Search for other papers by Olan Suwan-apichon in
Current site
Google Scholar
PubMed
Close
View More View Less
Restricted access

ABSTRACT.

This report is on a 45-year-old male patient without underlying disease who presented with a Burkholderia pseudomallei–caused keratoscleritis in his right eye. Slit-lamp examination revealed multiple, indistinct corneal infiltrations with subconjunctival/scleral abscesses. Corneal tissue culture was positive for B. pseudomallei and confirmed by mass spectrometry. The patient was treated with fortified ceftazidime, fortified gentamicin eyedrops, and intravenous ceftazidime injection. Penetrating keratoplasty, including intracameral ceftazidime injections, was undertaken due to corneal lesion worsening. Scleral debridement with subconjunctival ceftazidime injections were undertaken due to the progression of the scleral abscess. After 2 months, the corneal and scleral lesions were inactive, and the systemic and topical antibiotics were tapered. This is the first case report of B. pseudomallei–caused keratoscleritis with photography. The patient was seen in an endemic geographical area with multiple corneal infiltrations and subconjunctival/scleral abscess. Systemic and topical antibiotics accompanied with surgery should be considered.

Author Notes

Address correspondence to Onsiri Thanathanee, Department of Ophthalmology, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen 40002, Thailand. E-mail: onsirit@yahoo.com

Authors’ addresses: Onsiri Thanathanee, Korawin Charoensuk, Yuwarat Uthairat, Suparat Laohapitakvorn, Orapin Anutarapongpan, and Olan Suwan-apichon, Department of Ophthalmology, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand, E-mails: onsirit@yahoo.com, korawin.wn@gmail.com, y.uthairat@gmail.com, lecsuparat@gmail.com, orapin_159@yahoo.com, and osuwanapichon@hotmail.com.

Save